Maya

Hi John,

Ground glass opacities usually represent inflammation (and a few other things) whereas true fibrosis is defined by distinct features such as honeycombing, traction bronchiectasis, reticulations. So in your case it seems you have inflammatory changes caused by Covid and they will hopefully decrease. In some patients these changes progress…[Read more]

I think the understanding is that there is a genetic predisposition to IPF. I think familial IPF provides evidence for this. Research indicates that both genetic predisposition and environmental factors contribute to the risk of IPF and other idiopathic interstitial pneumonias.

Hi Pete,

Japanese scientists published a research article in early 2022 on the therapeutic effects of eperisone (muscle relaxant) on pulmonary fibrosis, showing that it is more effective in supressing fibroblast activity than current antifibrotic medication (pirfenidone and nintedanib). Eperisone also showed less adverse side effects. The…[Read more]

Hi Joe,

I think your pulmonologist diagnosed you with IPF because your CT scan showed a pattern of UIP (usual interstitial pneumonia) which is associated with IPF. That means that the distribution (subpleural, basal and bilateral) and features (reticulation) of scars point to UIP. I would add, as others already have, that there is absence of…[Read more]