Oral administration of omipalisib, an investigational inhibitor of PI3K and mTOR cellular signals, can reduce the activity of pro-fibrotic cells…
Alice Melão, MSc
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Articles by Alice Melão, MSc
Evotec and Galapagos will work together to develop a strategy to target fibrosis affecting several organs, the companies…
Canada’s SQI Diagnostics and the University Health Network (UHN) will work together to advance the development and approval…
A new subtype of immune cells carrying a unique genetic profile was identified and found to have an important role…
Galapagos has started the worldwide ISABELA Phase 3 program to evaluate the potential of GLPG1690 as a treatment for…
Preclinical data show that treatment with Nuformix’s investigational candidates within the NXP002 program can prevent fibrosis progression with…
Reduced Lung Function Linked to Increased Risk of Dementia, Cognitive Impairment, Study Reveals
Middle-age adults with reduced respiratory function have up to a 27% higher risk of developing dementia or cognitive impairment later…
Reduced levels of decorin proteins in the blood may be linked to a lower risk of death among patients with…
LOXL2 Inhibitor PXS-5382A Shows Potential to Treat IPF, Other Fibrotic Diseases in Phase 1 Trial
A new small molecule inhibitor of the LOXL2 enzyme, developed by Pharmaxis, is safe and holds potential to treat…
Poor Lung Function Before Starting Ofev Seen as Main Reason for Halting Use in UK Real-world Study
A greater decline in lung function prior to treatment start may lead idiopathic pulmonary fibrosis (IPF) patients to stop using…