News

Endeavor completes enrollment in Phase 2 trial testing ENV-101

A Phase 2a clinical trial to evaluate the safety and efficacy of ENV-101 (taladegib), Endeavor BioMedicines’ oral treatment for idiopathic pulmonary fibrosis (IPF), has completed patient enrollment. Top-line data from the study (NCT04968574), which enrolled 41 adults with mild-to-moderate IPF, ages 40 and older, at sites in…

Engineered stem cells could regenerate damaged tissue in PF

Scientists have developed a way to use engineered specialized stem cells to regenerate healthy airway tissues, offering a potential avenue for treating chronic lung diseases like pulmonary fibrosis (PF). In a pair of proof-of-concept preclinical studies published in Cell Stem Cell, scientists described how they engineered lung stem…

Supporters poised to ‘strike a pose’ for PF Awareness Month

Supporters are gearing up to mark Pulmonary Fibrosis Awareness Month, set aside every September, to call attention to the rare lung disease that affects more than 250,000 individuals in the U.S. and 400,000 in Europe. For its part, the Pulmonary Fibrosis Foundation (PFF), with its campaign theme “Embrace Your…

FDA approves new Esbriet generic from Lupin for IPF

The U.S. Food and Drug Administration (FDA) has approved a new generic version of Esbriet (pirfenidone) for idiopathic pulmonary fibrosis (IPF), according to an announcement by Lupin, the global pharmaceutical company that will market the medication. As with the brand name medicine, Lupin‘s generic will be available…

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