Steve Bryson, PhD, science writer —

Steve holds a PhD in biochemistry from the Faculty of Medicine at the University of Toronto, Canada. As a medical scientist for 18 years, he worked in both academia and industry, where his research focused on the discovery of new vaccines and medicines to treat inflammatory disorders and infectious diseases. Steve is a published author in multiple peer-reviewed scientific journals and a patented inventor.

Articles by Steve Bryson

Computer-analyzed CT Scans May Help With Early IPF Intervention

The risk of future lung-function decline and mortality in people with idiopathic pulmonary fibrosis (IPF) can be accurately predicted by a deep learning computer algorithm that evaluates CT scans, a study shows. Accurately determining the risk of progression would support early intervention before irreversible damage has occurred, the researchers…

Molecule Shows Potential to Treat PF in Surprising Manner

The small molecule TH5487 safely and effectively treated pulmonary fibrosis (PF) in a mouse model, a study reported. Although TH5487 is known to block the activity of the DNA repair enzyme OGG1, its anti-fibrotic effects occurred, in part, by reducing the production of OGG1 itself. According to researchers, these…

Aramchol Has Significant Anti-fibrotic Effects in IPF Mouse Model

Aramchol, an investigational therapy for idiopathic pulmonary fibrosis (IPF), demonstrated significant anti-fibrotic effects in a mouse model. The therapy, developed by Galmed Pharmaceuticals, is currently being evaluated in a Phase 3 clinical trial in people with nonalcoholic steatohepatitis, or NASH, a type of fatty liver disease characterized by…

Ofev for PF-ILD Now Reimbursed in 7 regions of Canada

Ofev (nintedanib), a medicine approved to treat progressive fibrosing interstitial lung disease (PF-ILD), now is available for public reimbursement in Ontario, Quebec, New Brunswick, Newfoundland and Labrador, Alberta, and the Northwest Territories. The therapy also will be reimbursed through the Non-Insured Health Benefits (NIHB) program, which provides eligible First…

Plant Extract Reduced Signs of IPF in Mice

An extract of the plant Lemna minor L., also called duckweed, suppresses the signs and symptoms of idiopathic pulmonary fibrosis (IPF) in disease-induced mice, a study suggests. More research to evaluate dosing and oral availability is recommended, study  authors noted. “Pulmonary Protein Oxidation and Oxidative Stress…

Inhaled IPF Therapy LTI-03 Well-Tolerated in Healthy Volunteers

Lung Therapeutics’ LTI-03, an investigational inhaled therapy for idiopathic pulmonary fibrosis (IPF), was safe and well-tolerated in healthy volunteers, with no reports of serious adverse events (side effects) or discontinuations, according to a Phase 1a trial. “We are pleased that LTI-03 has passed this important safety milestone as…

Haduvio Succeeds at Easing Chronic Cough of IPF in Phase 2 CANAL Trial

The investigational oral therapy Haduvio (nalbuphine extended-release tablets) significantly reduced chronic cough in people with idiopathic pulmonary fibrosis (IPF), according to interim results from the proof-of-concept Phase 2 CANAL trial. Findings in 26 patients showed a mean 51.7% placebo-adjusted decline in daytime cough frequency with the treatment, meeting the…

FDA Gives Breakthrough Therapy Status to Oral BI-1015550 for IPF

The U.S. Food and Drug Administration (FDA) has given breakthrough status to Boehringer Ingelheim’s BI-1015550, an experimental oral therapy for idiopathic pulmonary fibrosis (IPF), based partly on the findings of a clinical trial in IPF patients. A breakthrough therapy designation works to speed the development and review of…

Your PF Community

Woman laying down reading

Visit the Pulmonary Fibrosis News forums to connect with others in the PF community.

View Forums