Author Archives: Margarida Azevedo, MSc

OFEV’s Effectiveness as IPF Treatment Confirmed in Analysis of Pooled Clinical Trial Data

Combined evidence from the TOMORROW and INPULSIS clinical trials confirms the safety and efficacy of OFEV (nintedanib, Boehringer Ingelheim) in slowing disease progression and greatly reducing acute exacerbations in patients with idiopathic pulmonary fibrosis (IPF), a study reported. The article detailing the pooled analyses of the clinical studies, “…

Donor Lungs Ready for Transplant Is Goal of Toronto Start-up Supported by $2.6M from XENiOS

Medical device company XENiOS recently announced that it has invested $2.6 million in XOR-Labs Toronto, a spin-off of Toronto General Hospital at University Health Network (UHN), a world-leading center for lung transplantation. The startup company’s organ repair technology has the potential to help thousands of patients suffering from respiratory diseases, including pulmonary…

IPF Patients’ Likelihood of a Lung Transplant May Be Evident in Pulmonary Artery Size

Researchers investigating pulmonary artery size in idiopathic pulmonary fibrosis (IPF) patients have found that the pulmonary artery:ascending aorta diameter (PA:A) ratio could predict IPF clinical outcome, representing a potential new tool for stratifying patients to identify those most at risk. The study, “Pulmonary artery size as a predictor of outcomes in idiopathic…

IPF Patients Taking High-dose Steriods for Acute Exacerbations May Have Poor Outcomes

Idiopathic pulmonary fibrosis patients experiencing acute exacerbations (IPF-AE) who have a history of immunosuppression and high-dose steroid use are likely to have measurably worse survival outcomes than IPF-AE patients not under such treatment, a new study reported. The research article, “Survival in Idiopathic pulmonary fibrosis acute exacerbations: the non-steroid approach,” was published…

Pulmonary Fibrosis Among Top Projects in Expanding Research Partnership

MedImmune, AstraZeneca’s biologic research and development arm, announced that it is expanding its collaboration with the University of California, San Francisco (UCSF), to focus on basic research and translational sciences into diseases involving the Respiratory, Inflammation and Autoimmunity (RIA) fields. The partnership continues joint work begun in 2014, and the two will initiate about a half-dozen research projects…

Reata Enrolls First Patient in Clinical Trial for ILD Associated Pulmonary Hypertension

Reata Pharmaceuticals recently announced the recruitment of the first patient with pulmonary hypertension associated with interstitial lung disease (PH-ILD) in their Phase 2 LARIAT clinical trial evaluating the efficacy, safety, and tolerability of experimental therapy bardoxolone methyl in the treatment of patients with pulmonary hypertension (PH). The recent enrollment is part of…

IPF Study Focuses on Patient and Caregiver Needs Beyond Treatment

In a new study, researchers described the insights and perspectives of patients and caregivers regarding the clinical progression of idiopathic pulmonary fibrosis (IPF), and the needs of both at different disease stages. Their article, titled “The care needs of patients with idiopathic pulmonary fibrosis and their carers (CaNoPy): results of a qualitative…