Author Archives: Marisa Wexler MS

Iron Buildup in Lungs Can Drive Fibrosis, Study Finds

Abnormal buildup of iron in the lungs can cause lung fibrosis (scarring), and targeting this accumulation could be a therapeutic strategy for people with pulmonary fibrosis, a new study suggests. The study, “Critical role for iron accumulation in the pathogenesis of fibrotic lung disease,” was published in …

CRV431 Lowers Production of Collagen and Fibronectin in Several Cell Types

Hepion Pharmaceuticals‘ CRV431 lowers the production of fibrosis-associated proteins in a variety of cell types, including lung cells, new data from the company show. CRV431 is a small molecule being developed as an investigational treatment for non-alcoholic steatohepatitis (NASH) and viral hepatitis-induced liver disease. Both of these conditions are…