Research and Development
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Clusterin Protein Can Both Protect Against and Promote Fibrosis
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Clusterin Protein Can Both Protect Against and Promote Fibrosis
Cells’ attempts to limit fibroblast proliferation by lowering the levels of a protein called clusterin in lung fibroblasts of pulmonary fibrosis patients were found to be an insufficient strategy against fibrosis development in a recent study.
Researchers, in fact, observed that decreasing clusterin leads to a deposition of extracellular matrix proteins, which then actually contributes to fibrosis.
The study, “Diverse functions of clusterin promote and protect against the development of pulmonary fibrosis,” was published in the journal Scientific Reports.
You can read more about the study here: “Clusterin Protein in Lungs Can Both Protect Against and Promote Fibrosis, Study Shows“
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