Review Study Does Not Recommend Adding Antibiotics to Standard IPF Care

Adding co-trimoxazole or doxycycline — two broad-spectrum antibiotics — to standard care does not significantly slow lung function decline or prolong survival in people with idiopathic pulmonary fibrosis (IPF), a review study has found. This approach was instead associated with a higher risk of side effects, specifically gastrointestinal issues.

Adding Antibiotics to Standard Care Fail to Show Benefit in Large IPF Trial

Adding two broad spectrum antibiotics — co-trimoxazole or doxycycline — to standard care does not significantly delay hospitalization or prolong survival in adults with idiopathic pulmonary fibrosis (IPF), according to data from one of the largest clinical trials in IPF. While several studies have shown that changes in lung…