TGen Will Use Big Memory Technology to Accelerate IPF Research

The Translational Genomics Research Institute (TGen) will use a big-memory technology, called MemVerge Memory Machine Big Memory virtualization software, to accelerate research on the cellular mechanisms underlying idiopathic pulmonary fibrosis (IPF). “MemVerge Memory Machine has quickly resulted in research value for TGen,” Jonathan Jiang, chief operating officer of…

Scientists Create Cell Atlas Containing Gene Activity Information of More Than 300,000 Lung Cells from IPF and COPD Patients

Scientists created an online cell atlas containing information on the gene activity of more than 300,000 lung cells taken from patients with idiopathic pulmonary fibrosis (IPF) and chronic obstructive pulmonary disease (COPD). The new atlas adds to the knowledge of the complex cellular and molecular mechanisms involved…

World’s First Single-cell Sequencing Atlas Available for Drug Discovery in IPF

IPF Cell Atlas, the world’s first single-cell sequencing atlas for idiopathic pulmonary fibrosis (IPF), is now available to the public to advance research into new treatments for the condition. This comprehensive catalogue of the complexity and diversity of 35 distinct cellular populations that are abnormal in IPF patients,…

Gene Activity Analysis of IPF Lung Cells Pinpoints Abnormalities, Opens Way to Targeted Treatments

Wide access to potential molecular drug targets to treat pulmonary fibrosis is now possible, as researchers have mapped the complete set of genes active in individual lung cells from patients with idiopathic lung fibrosis and from healthy people. The analysis, called single-cell RNA sequencing, also made it possible to single out several…