What You Need to Know About Esbriet

Esbriet (pirfenidone), is an anti-fibrotic drug used in the treatment of patients with mild to moderate idiopathic pulmonary fibrosis (IPF). It’s made by the pharmaceutical company, Genentech.

Find out more about Esbriet for treating idiopathic pulmonary fibrosis.

A study by researchers at the University of Wisconsin found that the use of Esbriet could prolong the lives of patients with IPF by slowing down the progression of lung damage. The drug was approved by the FDA as a therapy for IPF in 2014.

It also found that Esbriet can decrease lung function decline in some patients. In clinical trials, the forced vital capacity tests (FVC) which measure lung function only deteriorated by less than 10 percent for 47.9 percent of participants according to lungdiseasenews.com, leading to fewer deaths from the disease.

According to Genentech, there are some side effects associated with Esbriet, the drug can make skin sensitive to the sun and ultraviolet rays from sunlamps and tanning beds, it can also cause mild reactions such as tiredness, headaches, respiratory infections, sinus infections, dizziness, and weight loss. More serious risks include liver involvement and stomach problems such as diarrhea, constipation, abdominal pain, heartburn, indigestion, nausea, and vomiting.

A study finds that Esbriet can prolong the lives of IPF patients.

Pulmonary Fibrosis News is strictly a news and information website about the disease. It does not provide medical advice, diagnosis or treatment. This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or another qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.


  1. Ron Cade says:

    I chose Esbriet over another drug. What does it take to get approval to be prescribed Esbriet? I have Tri Care for Life Insurance using Express Scripts or E Scripts for prescription medicines. My doctors request for approval went out on 3-24-17.

  2. My Husband did very well on Esbriet. His lung function went up 28% over time. He has no adverse affects. He went back to work and was fairly active. He found he didn’t need his O2 as much. I gave hime many other things to keep him healthy and he amazed us all. Unfortunately he was killed by an unmarked city vehicle so we could not continue with his therapy.

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