10 Drug Approvals That Changed the Future of Medicine


When people think of wonder drugs they think back to Alexander Fleming’s penicillin, the world’s first antibiotic. They may also think of aspirin, used as a painkiller and also as an anti-clotting agent for patients with a high risk of stroke or heart failure.

But there are thousands of drugs that have changed the course of history, saving lives and enhancing the quality of life for millions of people around the world.

Here are some of the biggest approvals in the last 10 years:

Ofev (nintedanib)
Ofev is an anti-fibrotic drug used for the treatment of idiopathic pulmonary fibrosis (IPF). It was approved by the FDA in October 2014 and works by inhibiting certain enzymes that promote the production of collagen which contributes to fibrosis of the lungs, slowing down the progression of the disease.

MORE: First patient enrolled in a trial of Ofev for progressive fibrosing interstitial lung disease. 

Esbriet (pirfenidone)
Esbriet was approved by the FDA in October 2014 to treat mild to moderate cases of idiopathic pulmonary fibrosis (IPF). Esbriet is both anti-fibrotic and anti-inflammatory so helps to slow down fibrosis of the lungs as well as reduce inflammation, helping to extend and improve the quality of life for patients with the disease.

MORE: Esbriet can prolong patients lives, several studies find.

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