Author Archives: Diana Campelo Delgado

Calprotectin May Be Biomarker of IPF Severity

Calprotectin may serve as a blood biomarker for disease severity in patients with idiopathic pulmonary fibrosis (IPF), a new study indicates. Calprotectin blood levels are significantly higher in IPF patients and show a correlation with measures of lung function. The study, “Serum calprotectin as new biomarker for disease…

Macrophages Stimulate Nerve-associated Scarring in PF, Study Shows

Immune cells called macrophages can stimulate nerve-associated lung scarring (fibrosis) in pulmonary fibrosis (PF), a study reports. Its findings suggest that antagonists (or inhibitors) of alpha-1 adrenergic nerve receptors may be a potential avenue for PF treatment. The study, “Macrophage-derived netrin-1 drives adrenergic nerve–associated lung fibrosis,”…

Dosing Begins in 2nd Phase 3 Trial of Antibody Treatment for IPF

Dosing has begun in a second Phase 3 trial testing FibroGen’s investigational antibody pamrevlumab in treating idiopathic pulmonary fibrosis (IPF). Still recruiting eligible patients at sites in three European countries — Georgia, Italy, and Hungary — and in Lebanon, the ZEPHYRUS-2 study (NCT04419558) is expected to enroll 340 people,…

Winners of 2020 Innovation Challenge for PF Announced

The nonprofit Three Lakes Foundation and the healthcare incubator MATTER announced the four winners of the 2020 Innovation Challenge, an initiative that promotes advancements in the way pulmonary fibrosis (PF) is diagnosed, treated, and managed. Winners of the challenge will receive a monetary award…