Author Archives: Forest Ray PhD

Peptide-coated Nanoparticles Limit Damage of IPF, Early Study Finds

Tiny particles, or nanoparticles, coated with a peptide called GSE4 prevented some features of idiopathic pulmonary fibrosis (IPF) and eased others in a rat model of this disease, scientists report. No harmful effects were associated with the use of these GSE4-loaded nanoparticles in the animals, the team added, suggesting they should…

Preclinical Study Will Probe Potency of Cymerus MSCs

Cynata Therapeutics will begin a preclinical study to investigate the mechanisms underlying the high potency of its cell therapy, Cymerus mesenchymal stem cells (MSCs), in treating lung diseases such as idiopathic pulmonary fibrosis (IPF). In an earlier study, the investigational therapy was able…

New Lung-on-a-Chip Could Allow for Personalized PF Treatment

A new lung-on-a-chip recreates complex lung structures using a patient’s own cells, providing a more precise model for studying disorders such as pulmonary fibrosis (PF), a study reported. This second-generation model is expected to give researchers with a powerful new way to conduct basic lung research, and a faster,…

1st Patient Enrolled in Trial Testing Ofev on Post-COVID-19 PF

The first patient has enrolled in a clinical trial to understand the effect of Ofev (nindetanib) on adults who developed pulmonary fibrosis (PF) following acute lung injury from COVID-19 infection. “A significant percentage of COVID-19 patients with acute lung injury may develop lung fibrosis based on clinical…