Treatment with regulatory T-cells (Tregs), a subset of cells from the immune system, is able to resolve lung fibrosis in a mouse model of idiopathic pulmonary fibrosis (IPF), according to researchers. Their findings support additional investigation of cell-based therapies to treat IPF in…
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At least 800 people representing some 45 countries are soon expected to gather in Austria’s capital city, Vienna, for ECRD 2018, the 9th European Conference on Rare Diseases and Orphan Products. The May 10-12 meeting is sponsored by Eurordis, the Paris-based group that defines itself as a “patient-driven alliance”…
A combined treatment, pirfenidone and rapamycin, worked to prevent fibrosis in lung fibroblasts from patients with idiopathic pulmonary fibrosis, new research showed, suggesting a possibly more effective way of treating IPF. The study, “Anti-fibrotic effects of pirfenidone and…
The Hastings Foundation has donated $12.5 million to the University of Southern California (USC) Hastings Center for Pulmonary Research to help advance research and development of new strategies to treat idiopathic pulmonary fibrosis and other lung diseases. This second donation follows a previous gift of $7.5 million in 2014,…
Transplantation of stem cells derived from adipose (fat) tissue in an animal model of silica dust-induced pulmonary fibrosis led to remission of the disease, as well as a reduction in inflammation and cell death, a new study shows. The study reporting the findings, “Transplantation of adipose-derived mesenchymal…
Scientists found that a special kind of white blood cell could potentially be stimulated to migrate to the lungs of idiopathic pulmonary fibrosis (IPF) patients and help repair fibrosis damage. They showed how this process occurs naturally in mice with lung fibrosis. The study, “TRAIL-Dependent Resolution…
Treatment with plant-derived aloperine reduces the severity of lung injury in a mouse model of pulmonary fibrosis, a new Chinese study reports. The research, “Aloperine Protects Mice against Bleomycin-induced Pulmonary Fibrosis by Attenuating Fibroblast Proliferation and Differentiation,” was published in the journal Scientific Reports. Idiopathic PF…
The digital healthcare company patientMpower recently released a new platform called patientMpower for Lung Transplant for patients with pulmonary fibrosis (PF) and other conditions who have received a lung transplant. In January, patientMpower was one of three winners of the $1 million IPF Catalyst Challenge, an award given to projects focused on…
The rate of decline in lung function in patients with idiopathic pulmonary fibrosis (IPF) before they are treated with Genentech‘s Esbriet (pirfenidone) influences the effects of the medication, researchers have found. Patients classified as rapid progressors, who experience accelerated declines in lung function, benefited more from Esbriet…
AdAlta has changed the structure of its lead therapy candidate for AD-114, for the treatment of pulmonary fibrosis. The new product, renamed AD-214, has enhanced activity and improved stability compared to AD-114, allowing a better outcome, according to AdAlta. AD-214 retains key features of its precursor, as it…
