Posts by: Patricia Inacio

Esbriet, News

Treatment with Esbriet (pirfenidone) slows the worsening of breathlessness in patients with more severe idiopathic pulmonary fibrosis (IPF), a post-hoc analysis of the ASCEND and CAPACITY trials shows. The ... Read more

June 12, 2019June 12, 2019

Certain Blood Protein Levels May Predict Mortality Risk After Sudden Disease Worsening in IPF, Study Suggests

News

Increased levels of specific proteins found in blood, namely C-reactive protein, lactate dehydrogenase, and total cholesterol, may predict the risk of mortality after acute exacerbation in idiopathic pulmonary fibrosis ... Read more

May 21, 2019May 22, 2019

Experimental IPF Therapy Safe and Well-tolerated, Ongoing Phase 1 Study Shows

News

Bridge Biotherapeutics’ investigational therapeutic candidate BBT-877 for idiopathic pulmonary fibrosis (IPF) was found to be safe and well-tolerated in the single-ascending dose phase of a Phase 1 trial with healthy volunteers, the ... Read more

May 10, 2019

Herbal Compound Rosavin May Help Reduce PF-related Scarring, Inflammation, Mouse Study Suggests

News

Rosavin, an active compound found in the plant Rhodiola rosea, commonly known as golden root or Aaron’s rod, can prevent pulmonary fibrosis (PF) manifestations in mice, a study has ... Read more

May 6, 2019May 6, 2019

Cigarette Smoke and Lipopolysaccharides Aggravate Lung Fibrosis, Mouse Study Suggests

News

Exposure to cigarette smoking and lipopolysaccharides, components of the cell wall of certain bacteria, can lead to more severe lung fibrosis, a mouse study shows. The study, “Cigarette smoke ... Read more

April 29, 2019April 29, 2019

Long Non-coding RNAs Regulate Lung Fibroblasts’ Inflammation, Proliferation, Study Shows

News

Proliferation and inflammation of human lung fibroblasts is controlled by small RNA molecules called long non-coding RNAs, a study reports. The study, “Long intergenic non-coding RNAs regulate human lung ... Read more

April 17, 2019April 17, 2019

Rare Gene Variants Linked to Worse Lung Transplant Outcomes in PF Patients

News

Rare variants in genes that regulate the end regions of chromosomes — called telomeres — are linked with worse survival rates after lung transplant in pulmonary fibrosis (PF) patients, ... Read more

April 10, 2019

High Levels of Vimentin Protein Linked to Lung Fibrosis, Study Shows

News

High levels of the protein vimentin in the lung tissue of patients with idiopathic pulmonary fibrosis (IPF) contribute to disease progression, an early study’s results show. Inhibiting vimentin can prevent fibroblasts — ... Read more

April 8, 2019

Secondary Insurance Coverage Boosts Adherence to Treatment with Ofev, Esbriet, Study Finds

Esbriet, News

Although patients with idiopathic pulmonary fibrosis (IPF) who take Ofev (nintedanib) or Esbriet (pirfenidone) have similar clinical outcomes, adherence to treatment is higher among those who have secondary insurance coverage, ... Read more

March 26, 2019April 4, 2019

Esbriet Safe and Effective for Patients with Advanced Idiopathic Pulmonary Fibrosis, Trial Suggests

Esbriet, News

A post-hoc analysis of the Phase 3 RECAP trial shows that long-term treatment with Esbriet (pirfenidone) is safe and similarly effective in patients with advanced idiopathic pulmonary fibrosis (IPF) as in ... Read more

Posts by: Patricia Inacio

Patricia Inacio

Esbriet Helps Halt Breathlessness Symptoms in Severe IPF, Analysis of Multiple Trials Shows

Certain Blood Protein Levels May Predict Mortality Risk After Sudden Disease Worsening in IPF, Study Suggests

Experimental IPF Therapy Safe and Well-tolerated, Ongoing Phase 1 Study Shows

Herbal Compound Rosavin May Help Reduce PF-related Scarring, Inflammation, Mouse Study Suggests

Cigarette Smoke and Lipopolysaccharides Aggravate Lung Fibrosis, Mouse Study Suggests

Long Non-coding RNAs Regulate Lung Fibroblasts’ Inflammation, Proliferation, Study Shows

Rare Gene Variants Linked to Worse Lung Transplant Outcomes in PF Patients

High Levels of Vimentin Protein Linked to Lung Fibrosis, Study Shows

Secondary Insurance Coverage Boosts Adherence to Treatment with Ofev, Esbriet, Study Finds

Esbriet Safe and Effective for Patients with Advanced Idiopathic Pulmonary Fibrosis, Trial Suggests

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