Posts by: Patricia Inacio

Pharmaxis’ first small molecule inhibitor of LOXL2 (lysyl oxidase like 2), an enzyme that promotes fibrosis in the lungs of idiopathic pulmonary fibrosis (IPF) patients, was found safe and well-tolerated ... Read more

September 28, 2018October 2, 2018

Esbriet and Ofev Show Significant Benefits in Real-Life Clinical Setting

Esbriet, News

Treatment with Esbriet (pirfenidone) or Ofev (nintedanib) significantly slowed the progression of idiopathic pulmonary fibrosis (IPF) in a real-life clinical setting, an Italian study reported. The study, “Pirfenidone and Nintedanib ... Read more

September 7, 2018September 11, 2018

Low Levels of HOPX Protein in Lung Impair Cell Regeneration, Worsen IPF, Study Suggests

News

Low levels of the homeobox only protein x (HOPX) in lung samples from idiopathic pulmonary fibrosis (IPF) patients are linked to lung function decline and disease progression, a new ... Read more

August 24, 2018August 28, 2018

PF Gene Therapy That Extends Life of Lung Cells Not Linked to Increased Cancer Risk, Study Shows

News

A gene therapy designed to fight pulmonary fibrosis (PF) by extending the lifespan of lung cells has been found safe and does not cause or increase the risk of ... Read more

August 21, 2018August 24, 2018

Treatment with Plant Pigment Quercetin Reduces Lung Fibrosis in Mouse Model, Study Reports

News

A plant-based medicine called quercetin reversed pulmonary fibrosis in a mouse model likely by reducing the burden of growth-arrested and fibrosis-promoting cells, called senescent cells, in the animals’ lungs, ... Read more

June 26, 2018June 26, 2018

‘Lung-on-a-Leaf’ May Aid Studies into Pulmonary Diseases, From Fibrosis to Inflammation

News

The Arizona Biomedical Research Commission awarded a $750,000 grant to researchers at University of Arizona (UA) College of Medicine for their innovative, plant-based model system — a “lung” growing on a ... Read more

June 15, 2018June 15, 2018

American Lung Association’s Better Breathers Club Welcomes PF Patients and Caregivers

News

The American Lung Association’s Better Breathers Club is now extending its resources and support network to patients with pulmonary fibrosis (PF), among others with chronic lung diseases. Getting a PF diagnosis ... Read more

June 8, 2018June 8, 2018

Double Lung Transplant Better for Pulmonary Fibrosis Patients Younger than 70, Study Shows

News

Double lung transplants are linked to significantly higher survival rates than single lung transplants among pulmonary fibrosis patients younger than 70, a retrospective study shows. The study, “Single versus ... Read more

June 1, 2018June 1, 2018

New Lung-on-a-chip Technology Captures Fibrosis Progression and May Speed Treatment Discovery, Study Reports

Esbriet, News

A new lung-on-a-chip technology models the mechanical changes that occur in the lungs during idiopathic pulmonary fibrosis, possibly allowing for a faster and less expensive screening of potential new ... Read more

May 29, 2018May 29, 2018

#ATS2018 – Esbriet Lowers Risk of Seasonal IPF Flares Leading to Hospitalizations, Phase 3 Data Show

Esbriet, News

Seasonal flares of disease activity that can lead to idiopathic pulmonary fibrosis (IPF) patients being hospitalized, especially in the winter months, appear to be effectively countered by treatment with Esbriet (pirfenidone) compared ... Read more

Posts by: Patricia Inacio

Patricia Inacio

Pharmaxis’ LOXL2 Inhibitor Shows Positive Results in Phase 1 Trial in Healthy Volunteers

Esbriet and Ofev Show Significant Benefits in Real-Life Clinical Setting

Low Levels of HOPX Protein in Lung Impair Cell Regeneration, Worsen IPF, Study Suggests

PF Gene Therapy That Extends Life of Lung Cells Not Linked to Increased Cancer Risk, Study Shows

Treatment with Plant Pigment Quercetin Reduces Lung Fibrosis in Mouse Model, Study Reports

‘Lung-on-a-Leaf’ May Aid Studies into Pulmonary Diseases, From Fibrosis to Inflammation

American Lung Association’s Better Breathers Club Welcomes PF Patients and Caregivers

Double Lung Transplant Better for Pulmonary Fibrosis Patients Younger than 70, Study Shows

New Lung-on-a-chip Technology Captures Fibrosis Progression and May Speed Treatment Discovery, Study Reports

#ATS2018 – Esbriet Lowers Risk of Seasonal IPF Flares Leading to Hospitalizations, Phase 3 Data Show

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