Posts by: Patricia Inacio, PhD

Patricia Inacio, PhD

Patricia holds a Ph.D. in Cell Biology from University Nova de Lisboa, and has served as an author on several research projects and fellowships, as well as major grant applications for European Agencies. She has also served as a PhD student research assistant at the Department of Microbiology & Immunology, Columbia University, New York.

November 19, 2019November 19, 2019

Model of Pulmonary Fibrosis Details Gene Changes at Specific Disease Stages, Study Reports

News

A model of the human lung constructed with the help of tissue samples from 10 idiopathic pulmonary fibrosis (IPF) patients details changes in gene activity that precede evident fibrosis, a ... Read more

November 12, 2019November 13, 2019

Occupational Dust Exposure May Not Hinder Effectiveness of Anti-fibrotic Therapies, Study Suggests

News

Exposure to dust in the workplace for 10 years or longer seems to have no detrimental effect on the response of patients with idiopathic pulmonary fibrosis (IPF) to anti-fibrotic ... Read more

October 28, 2019October 28, 2019

Lung Cancer Patients with IPF and Emphysema at Higher Risk of Flares, Study Says

News

People with non-small cell lung cancer (NSCLC) who also have pulmonary fibrosis and emphysema are at a greater risk of acute flares following cancer treatment that includes chemotherapy, surgery, ... Read more

October 15, 2019October 15, 2019

NIH Director’s New Innovator Award Funds Research to Develop New Models to Study IPF

News

April Kloxin, PhD, has received the 2019 National Institutes of Health (NIH) Director’s New Innovator Award to develop next-generation materials and tools to help accelerate research on idiopathic pulmonary fibrosis (IPF). ... Read more

September 20, 2019September 25, 2019

Citryll, Lonza Team up to Develop Antibody for Pulmonary Fibrosis, Other Inflammatory Diseases

News

Citryll and Lonza have teamed up to develop Citryll’s candidate antibody, called CIT-013, as a therapy for inflammatory diseases, including idiopathic pulmonary fibrosis (IPF) and rheumatoid arthritis, the companies ... Read more

September 4, 2019September 4, 2019

Protein on Surface of Immune Cells May Drive Inflammation in Pulmonary Fibrosis, Study Suggests

News

Immune cells can sense the mechanical forces at work in the lungs via a gate called PIEZO1, and deleting this gene in immune cells led to worse lung infections, ... Read more

August 20, 2019August 28, 2019

Targeting Cells in Autophagy Process May Be Path to Halting Fibrosis, Study Suggests

News

Impaired autophagy — cells’ self-cleansing process — in the lungs’ epithelial cells may activate their epithelial-mesenchymal transition (EMT), a process crucial to the progression of fibrosis, according to a new ... Read more

August 5, 2019August 5, 2019

Mortality Rate Due to IPF Has Risen in United Kingdom, Data Show

News

The mortality rate due to idiopathic pulmonary fibrosis (IPF) increased from 1979 to 2016 in the United Kingdom, a retrospective analysis shows. Researchers estimate that death due to IPF ... Read more

July 31, 2019August 2, 2019

New Clinical Model to Manage Terminally Ill IPF Patients Decreases Suffering and Costs

News

A new clinical model for terminal idiopathic pulmonary fibrosis (IPF) that allows patients to receive treatment at home has increased patient satisfaction, decreased hospital deaths, led to better symptom ... Read more

July 26, 2019July 26, 2019

Certain Matrix Metalloproteinases Are Potential Biomarkers for PF in Rare Genetic Disorder, Study Suggests

News

Increased activity of certain matrix metalloproteinases (MMPs), enzymes that regulate cell behavior, may explain the risk for developing aggressive pulmonary fibrosis in people with Hermansky-Pudlak syndrome (HPS), a rare ... Read more

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