Posts by: Patricia Inacio

Esbriet, News

Esbriet (pirfenidone) can improve survival rates of idiopathic pulmonary fibrosis (IPF) patients by 30 percent, a real-world retrospective analysis shows. The study, “Pirfenidone improves survival in IPF: results from a ... Read more

November 27, 2018November 27, 2018

Pre-existing PF Increases Risk of Lung Inflammation Among Lung Cancer Patients Using Opdivo or Keytruda, Study Suggests

News

Pulmonary fibrosis significantly increases the risk of severe pneumonitis (inflammation of lung tissue) among patients with lung cancer who were treated with Opdivo or Keytruda, a retrospective study suggests. The study “Pre-existing ... Read more

November 14, 2018November 20, 2018

Ofev Maintains Effectiveness in Advanced IPF Patients, Real-world Study Shows

News

Ofev (nintedanib) shows a similar ability to reduce lung function decline in patients with advanced idiopathic pulmonary fibrosis (IPF) as those with milder disease, according to a real-world clinical study. ... Read more

November 7, 2018November 13, 2018

BML-111 Found to Suppress Lung Fibrosis in Mouse Model by Inhibiting Signaling Molecules

News

BML‐111, a potent activator of the natural anti-inflammatory lipoxin A4 receptor, protects lungs from fibrosis by inhibiting fibroblast activation and decreasing the levels of inflammatory signaling molecules, a mouse ... Read more

October 15, 2018November 19, 2018

Pharmaxis’ LOXL2 Inhibitor Shows Positive Results in Phase 1 Trial in Healthy Volunteers

News

Pharmaxis’ first small molecule inhibitor of LOXL2 (lysyl oxidase like 2), an enzyme that promotes fibrosis in the lungs of idiopathic pulmonary fibrosis (IPF) patients, was found safe and well-tolerated ... Read more

September 28, 2018October 2, 2018

Esbriet and Ofev Show Significant Benefits in Real-Life Clinical Setting

Esbriet, News

Treatment with Esbriet (pirfenidone) or Ofev (nintedanib) significantly slowed the progression of idiopathic pulmonary fibrosis (IPF) in a real-life clinical setting, an Italian study reported. The study, “Pirfenidone and Nintedanib ... Read more

September 7, 2018September 11, 2018

Low Levels of HOPX Protein in Lung Impair Cell Regeneration, Worsen IPF, Study Suggests

News

Low levels of the homeobox only protein x (HOPX) in lung samples from idiopathic pulmonary fibrosis (IPF) patients are linked to lung function decline and disease progression, a new ... Read more

August 24, 2018August 28, 2018

PF Gene Therapy That Extends Life of Lung Cells Not Linked to Increased Cancer Risk, Study Shows

News

A gene therapy designed to fight pulmonary fibrosis (PF) by extending the lifespan of lung cells has been found safe and does not cause or increase the risk of ... Read more

August 21, 2018August 24, 2018

Treatment with Plant Pigment Quercetin Reduces Lung Fibrosis in Mouse Model, Study Reports

News

A plant-based medicine called quercetin reversed pulmonary fibrosis in a mouse model likely by reducing the burden of growth-arrested and fibrosis-promoting cells, called senescent cells, in the animals’ lungs, ... Read more

June 26, 2018June 26, 2018

‘Lung-on-a-Leaf’ May Aid Studies into Pulmonary Diseases, From Fibrosis to Inflammation

News

The Arizona Biomedical Research Commission awarded a $750,000 grant to researchers at University of Arizona (UA) College of Medicine for their innovative, plant-based model system — a “lung” growing on a ... Read more

Posts by: Patricia Inacio

Patricia Inacio

Esbriet Extends IPF Patient Survival, Real-world Study Reports

Pre-existing PF Increases Risk of Lung Inflammation Among Lung Cancer Patients Using Opdivo or Keytruda, Study Suggests

Ofev Maintains Effectiveness in Advanced IPF Patients, Real-world Study Shows

BML-111 Found to Suppress Lung Fibrosis in Mouse Model by Inhibiting Signaling Molecules

Pharmaxis’ LOXL2 Inhibitor Shows Positive Results in Phase 1 Trial in Healthy Volunteers

Esbriet and Ofev Show Significant Benefits in Real-Life Clinical Setting

Low Levels of HOPX Protein in Lung Impair Cell Regeneration, Worsen IPF, Study Suggests

PF Gene Therapy That Extends Life of Lung Cells Not Linked to Increased Cancer Risk, Study Shows

Treatment with Plant Pigment Quercetin Reduces Lung Fibrosis in Mouse Model, Study Reports

‘Lung-on-a-Leaf’ May Aid Studies into Pulmonary Diseases, From Fibrosis to Inflammation

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