News

Changes in Blood Cell Ratios Linked to Worse Outcomes

Idiopathic pulmonary fibrosis (IPF) patients showing greater changes in blood cell ratios often used as markers of inflammation are at higher risk of lung function decline, respiratory hospitalization, and death, according to a post-hoc analysis of data from several Phase 3 clinical trials. Notably, these associations were more pronounced…

Smoking, Oxygen Use Linked to Higher Hospitalization Risk in IPF

While receiving treatment at specialized centers lowers the risk of hospitalization among patients with idiopathic pulmonary fibrosis (IPF), being a former smoker and requiring oxygen therapy are both associated with a higher likelihood of hospitalization. These are some of the findings of multiple studies that Boehringer Ingelheim will…

Compound in Medicinal Herb Shows Anti-fibrotic Potential

Magnesium lithospermate B, a compound found in a traditional Chinese medicinal herb, eased several features of pulmonary fibrosis (PF) in a mouse model of the disorder. According to investigators, the anti-fibrotic effects of this plant compound were comparable to those of Esbriet (pirfenidone), an approved treatment for…

Galapagos Advances GLPG4617 Into Phase 2 Trial

In a move that refocuses its clinical pipeline, Galapagos is discontinuing the development of GLPG1205, its experimental therapy for idiopathic pulmonary fibrosis (IPF), and advancing its most recent IPF candidate, GLPG4617, into a Phase 2 clinical trial. These and other decisions toward a “more risk-balanced pipeline” are…

Vote Now for Breathless Ballad Challenge

Former New York Yankee and Grammy-nominated musician Bernie Williams will join musician, actress, and producer Queen Latifah, music duo The Bacon Brothers, singer-composer Paul Shaffer, and others to serve as a judge in the Breathless Ballad Challenge, a lyric competition that aims to raise awareness about idiopathic pulmonary…

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