Research and Development
This group unites PF patients, caregivers, researchers and medical professionals in a platform to... View more
Use of Aspirin.
-
Use of Aspirin.
Hello all,
I posted a comment on the use of aspirin on the IPF News ‘Research and development’ site, saying that I was going to start with low dose, 75mg, gastro resistant tablets.
Being aware of the Gastro-intestinal (GI) risks of taking aspirin in as a prophylactic, I thought, ‘is there another mechanism of administration’.
After some internet searching, I found that yes it has been investigated. A small trial using an aspirin paste preparation applied to tbe forearm, several days, while monitoring aspirin in the blood. Yes it worked, transfering at a slower absorbtion rate than tablets would. However, the GI irritation risks were equal to the oral route. I seems that it is the blood levels that have an effect on the GI tract mucosa making ulcers and intestinal damage just as likely.
I am in week 2 and intend to continue with caution. Monitoring gut sensations and stool colours. Also, note that I am on Nintedanib 2 x 100mg daily.
Will report progress.
Regards to all fellow IPF friends,
Joe
Log in to reply.