The investigational therapy LYT-100 (deupirfenidone) significantly slowed lung function decline in people with idiopathic pulmonary fibrosis (IPF), outperforming the standard of care therapy Esbriet. PureTech Health’s treatment candidate also caused fewer gastrointestinal side effects in patients. That’s according to top-line data from the ongoing Phase…
The holidays have arrived, which reminds of those passenger-side mirrors that read, “Objects in mirror are closer than they appear.” It wasn’t too long ago that the holidays seemed far away, yet here they are. After I was diagnosed with idiopathic pulmonary fibrosis (IPF) in 2017, my health…
Trevi Therapeutics announced that its ongoing Phase 2b clinical trial testing Haduvio (nalbuphine extended-release tablets) in people with idiopathic pulmonary fibrosis (IPF) who have chronic cough has reached 75% of its targeted patient enrollment. The Phase 2b CORAL trial (NCT05964335) is still seeking to recruit a…
Good grief! When I hear this two-word phrase, I often associate it with the cartoon character Charlie Brown. Otherwise, the words “good” and “grief” seldom seem to belong together. What do you do with grief amid the holiday season? If you’ve been reading my columns for some time,…
The first patient has been dosed in a Phase 2b clinical trial of Endeavor Biomedicines’ investigational oral therapy ENV-101 (taladegib) in people with idiopathic pulmonary fibrosis (IPF). WHISTLE-PF (NCT06422884) seeks to enroll around 200 adults in 14 countries. The first patient was dosed in Australia. The study’s launch…
Welcome to December. Wait, what? How is it December? Time seemed to move in slow motion during the height of the COVID-19 pandemic, and now it’s already the end of 2024. In 1974, the Rolling Stones released “Time Waits for No One.” One line sums it up: “Time…
Families will gather this week to celebrate Thanksgiving here in the U.S. But how do you safely navigate a large family gathering when colds, the flu, and COVID-19 are all circulating? When I was diagnosed with idiopathic pulmonary fibrosis (IPF) in 2017, a lot changed in my world.
The Pulmonary Fibrosis Foundation (PFF) has launched “PF Basics: Info for Newly Diagnosed Patients,” a new educational program to help patients with pulmonary fibrosis (PF) and interstitial lung disease get answers to the most pressing questions about their disease after a recent diagnosis. “We heard from patients and caregivers…
Since my diagnosis of idiopathic pulmonary fibrosis (IPF) in 2016, I’ve learned to manage my emotions about my illness. However, there are a few circumstances that make it nearly impossible for me to control how I feel, often causing me to erupt with rage and anger. One of those…
Do you know what a hack is? It’s a way of doing something more simply, efficiently, or effectively. Throughout my journey living with idiopathic pulmonary fibrosis (IPF), I’ve found a number of hacks that make my life easier. When I was diagnosed with IPF in January 2017, I…
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