World’s First Single-cell Sequencing Atlas Available for Drug Discovery in IPF

IPF Cell Atlas, the world’s first single-cell sequencing atlas for idiopathic pulmonary fibrosis (IPF), is now available to the public to advance research into new treatments for the condition. This comprehensive catalogue of the complexity and diversity of 35 distinct cellular populations that are abnormal in IPF patients,…

As parts of the world begin to partially open up again amid the COVID-19 pandemic, I can’t help but feel fearful and anxious. Those of us with chronic respiratory illnesses like idiopathic pulmonary fibrosis (IPF) must regularly take precautions to avoid getting sick throughout the entire year. However, the…

Algernon Pharmaceuticals has begun screening patients for its Phase 2 clinical trial investigating its repurposed compound NP-120 (ifenprodil) for the treatment of idiopathic pulmonary fibrosis (IPF) and associated chronic cough. The study (NCT04318704) will be conducted at three sites in Australia and two in New Zealand, all…

The protective tips of chromosomes, called telomeres, are shorter in men with idiopathic pulmonary fibrosis (IPF) than age-matched peers, and these changes seem to be linked to lower blood levels of the male hormone testosterone, a study reported. Further…

Rates of hospitalization and in-hospital mortality dropped significantly for people with idiopathic pulmonary fibrosis (IPF) in the U.S. between 2006 and 2016, and hospitalizations were most common in colder months, an analyses of disease trends found. The study, “Trends and…

I have always advocated for good mental health and promoted the importance of self-care. I preach regularly about this to friends, family, colleagues, and other patients with idiopathic pulmonary fibrosis (IPF). Since being diagnosed with this life-threatening lung disease, my physical health has been a priority. I do…

Single lung transplant patients with idiopathic pulmonary fibrosis (IPF) have a higher risk of developing lung cancer, according to a recent study — and these cancers are more likely to be diagnosed at an advanced stage and carry a worse prognosis. Thus, the researchers recommend prioritizing people with IPF…

A cell therapy approach based on transplanting a type of lung cells called type II alveolar cells halted scarring (fibrosis) in a rat model of idiopathic pulmonary fibrosis (IPF) with established disease. This anti-fibrotic effect was associated with a drop in lung levels of several fibrotic markers, the researchers said.

Treating acute exacerbations with the protein thrombomodulin (ART-123) in idiopathic pulmonary fibrosis (IPF) patients may be associated with short-term survival benefits, a review analysis reports. However, larger studies are needed to confirm these findings, the researchers noted. The study, “Efficacy…

As I sat in my mom’s hospital room on the day of her long-awaited discharge, I felt like we were bringing home a very fragile adult baby. Her body had been through a series of assaults starting with an acute exacerbation of IPF and ending with a double-lung transplant.