AGMB-447, an inhaled treatment for idiopathic pulmonary fibrosis (IPF) now being tested in a Phase 1 clinical trial, has been granted orphan drug designation by the U.S. Food and Drug Administration (FDA). The FDA gives this designation to therapies that may improve care for people with rare diseases,…
IPF treatment AGMB-447 granted FDA orphan drug status
I love to travel, and I’m grateful I can still do it. Despite the limitations caused by my idiopathic pulmonary fibrosis (IPF), travel sets my soul on fire and provides me with many reminders about the beauty of being alive. Back in January, I wrote about relating more…
I spent last week childproofing my home. No, my wife, Susan, and I aren’t expecting. Our granddaughters, Abigail and Charlotte, are coming with my son Christopher for a visit to our home. When I was diagnosed with idiopathic pulmonary fibrosis (IPF) in January 2017, there were no grandchildren…
The U.S. Food and Drug Administration (FDA) has granted its orphan drug designation to Alentis Therapeutics’ antibody-based therapy lixudebart (ALE.F02) for idiopathic pulmonary fibrosis (IPF). Orphan drug designation is given to support the accelerated development of investigational treatments for rare diseases, defined as those affecting fewer than 200,000…
I recently read a social media post from a patient who uses supplemental oxygen. They said they were unable to alert a family member in a neighboring room when the power went out, causing their oxygen to stop. Someone commented that if the patient had been on only 3 liters…
Endeavor BioMedicines’ ENV-101 improved lung function and reversed key signs of lung scarring in people with idiopathic pulmonary fibrosis (IPF), according to data from a completed Phase 2a trial. The results, which also showed the treatment had an acceptable tolerability profile, were presented in a late-breaking oral…
Keeping up with a regular exercise routine and a healthy diet can be hard as we get older. Between our career, family commitments, and social obligations, finding time for these habits tends to be challenging. Still, maintaining a healthy weight is important for our overall health, and may even…
I was diagnosed with idiopathic pulmonary fibrosis (IPF) in January 2017, at age 59, and received a bilateral lung transplant in July 2021. During a visit last week, my adult daughter Heather asked me a perplexing question: “Is the IPF gone now that you have new lungs?”…
The Pulmonary Fibrosis Foundation (PFF) said its two-year-old patient Community Registry achieved a “significant milestone” in its goal to drive more research and discoveries in pulmonary fibrosis (PF) and interstitial lung diseases (ILDs), reaching its 2,000th participant. The registry opened in July 2022 to provide scientists with…
When idiopathic pulmonary fibrosis (IPF) patients experience a worsening of symptoms, it’s often called an exacerbation. I didn’t know it at the time, but my diagnosis with IPF in January 2017 started me on an educational journey. My vocabulary was going to expand to include new…
