Music has always played a significant role in my life. From childhood choir performances to playing the trumpet in school bands, melodies have been a constant source of joy, solace, and self-expression. Despite the challenges posed by my pulmonary fibrosis (PF), music remains a trusty companion, offering a therapeutic…
The healing power of music on my journey with pulmonary fibrosis
This has been quite the week. I can sum it up in one word: grief, which must be one of the most unpredictable emotions we experience. When I was diagnosed with idiopathic pulmonary fibrosis (IPF) in January 2017, I made a conscious decision to “be positive in all…
LTI-03, an inhaled therapy for idiopathic pulmonary fibrosis (IPF) from Aileron Therapeutics, was able to reduce levels of several proteins known to promote tissue scarring in the first group of patients participating in a Phase 1b trial, data from the trial showed. The trial (NCT05954988) is assessing…
The life I once knew and loved drastically changed on April 7, 2016. On that day, I was diagnosed with idiopathic pulmonary fibrosis (IPF), a life-threatening and progressive lung disease for which there is no cure. Earlier this month, I marked my eighth anniversary of having IPF —…
“You’ll Never Walk Alone” was written by Richard Rodgers and Oscar Hammerstein II for the 1945 musical “Carousel.” Many others have performed the song over the years, and it’s even become the anthem for Liverpool Football Club in England. Most recently, I’ve enjoyed the version by…
Endeavor BioMedicines has raised $132.5 million toward the clinical development of its pipeline programs, including ENV-101, an investigational oral treatment for idiopathic pulmonary fibrosis (IPF). Results from a recent Phase 2a trial (NCT04968574) showed ENV-101 was generally well tolerated, reduced tissue scarring, or fibrosis, and improved lung…
When I was diagnosed with idiopathic pulmonary fibrosis (IPF) in 2017, I soon learned the cause and cure were mysteries yet to be solved. I know firsthand how difficult it can be to solve a mystery. Difficult, but seldom impossible. I worked my first career as a special…
Researchers have developed an inhalable prototype medicine that may be able to repair lung scarring caused by idiopathic pulmonary fibrosis (IPF) by stimulating the growth of stem cells directly in the lungs, a study reports. The study provides pharmacological proof of concept for an upcoming Phase 1 clinical trial…
The arrival of spring here in Virginia is both a blessing and a curse. Despite the improved weather, I think of it as pollen and mold season. As a longtime sufferer of seasonal allergies, I don’t need the gentle yellow-green tint on vehicles and patio furniture to remind me to…
Enrollment has been completed for a Phase 2b trial that’s testing LYT-100 (deupirfenidone), PureTech Health’s experimental therapy for idiopathic pulmonary fibrosis (IPF). The trial, called ELEVATE IPF (NCT05321420), is assessing the safety, efficacy, and dosing regimen of LYT-100 in 240 adults with IPF, compared with a placebo.
