The pharmaceutical company Humanetics will use a federal grant to fund a series of studies aimed at advancing the development of BIO 300 for idiopathic pulmonary fibrosis (IPF) — for one, testing the treatment candidate for its effectiveness in easing lung scarring, or fibrosis. BIO 300 is thought to…
Humanetics to use federal grant to advance BIO 300 as IPF treatment
Today is traditionally a day for trick-or-treating, haunted houses, pumpkin patches, hay rides, and of course, pumpkin “chunkin’”. I have always enjoyed Halloween, the scariest day of the year for many. I mentioned last week that my wife, Susan, and I host a Halloween costume party each year. Costumed partygoers and…
The U.S. Food and Drug Administration (FDA) has granted breakthrough therapy designation to BMS-986278, Bristol Myers Squibb’s investigational therapy for progressive pulmonary fibrosis (PF). Breakthrough therapy designation is intended to expedite the development and review of medicines for serious or life-threatening diseases. The decision is based on preliminary…
The pulmonary fibrosis (PF) community is not a stranger to stress. Regardless of your role, whether as a patient, caregiver, or transplant recipient, you’ve likely experienced it. The stress could be white coat syndrome or come from a test, procedure, or the many unknowns associated with living…
Use of cancer chemotherapy agents or rituximab to treat autoimmune diseases was associated with an increased risk of pulmonary fibrosis (PF) in people hospitalized with COVID-19, according to a large-scale U.S. study. Exposure to these medications, along with anti-inflammatory corticosteroids and amiodarone, used to treat certain heart rhythm disorders,…
Living with a chronic illness like idiopathic pulmonary fibrosis (IPF) is a multifaceted endeavor. It’s hard to fully describe just how many aspects of life the disease affects. Despite writing about it for seven years, there’s always something new I want to share with this community, because…
Have you ever had the nagging feeling that a gray cloud was hanging over your head? For the past three years and 10 months, I’ve felt such a cloud. It comes from being labeled and stigmatized for my disability. Stigma can be described as a deeply discrediting attribute that…
In a single month, I’ve had three vaccinations, three medical procedures requiring anesthesia, two lab tests, one dental appointment, one pentamidine treatment, one appointment at the pulmonary clinic, and one pulmonary function test. As I’ve noted before, life after lung transplant is busy with medical surveillance. I…
LYT-100, PureTech Health’s oral treatment candidate for idiopathic pulmonary fibrosis (IPF), was well tolerated among healthy older adults at doses leading to much higher amounts of active medication in the body than the approved dose of Esbriet (pirfenidone). That’s according to new data from Phase 1 clinical…
Amy Silverstein’s second memoir, “My Glory Was I Had Such Friends” (2017), left a lasting impression on me. It wasn’t just because of the way Silverstein’s devoted friends attended to her while she awaited a second heart transplant, or even how that story mirrored…
