A Phase 2a trial is recruiting people with idiopathic pulmonary fibrosis (IPF) to assess the effectiveness of GRI-0621, GRI Bio‘s investigational natural killer T-cell (NKT)-targeted therapy. The multicenter biomarker study, which was cleared to start by the U.S. Food and Drug Administration, is expected to have early results…
Phase 2a trial of natural killer T-cell therapy in IPF starts enrolling
‘Tis the season of giving, a time when the spirit of benevolence fills the air. During the holidays, we’re encouraged to give wholeheartedly and with grace, which creates an atmosphere of joy and peace. However, the season’s festivities prompt some reflection on the nature of giving. Why limit this…
I’ve been involved in equity issues for most of my adult life and have been an advocate for the rare disease community for decades. In the biblical story of David and Goliath in 1 Samuel 17, David had no intention of shying away from Goliath. Neither do I.
Trevi Therapeutics has launched a Phase 2b clinical trial testing therapeutic candidate Haduvio (nalbuphine extended-release tablets) for the treatment of chronic cough in people with idiopathic pulmonary fibrosis (IPF). The Phase 2b trial, CORAL (NCT05964335), plans to enroll about 160 adults with IPF and chronic cough. No…
Each month, Brad Dell, the director of community content at Bionews, the parent company of this website, curates a list of special days of recognition ranging from the whimsical to causes that have special meaning to both individuals and entire communities. From the whimsical side of the December list,…
The U.S. Food and Drug Administration (FDA) has given GRI Bio the green light to conduct a Phase 2 trial of its investigational natural killer T-cell (NKT)-targeted therapy, GRI-0621, in people with idiopathic pulmonary fibrosis (IPF). With the clearance of its investigational new drug (IND) application, the company…
When people first think about disease or disability, they usually go to the physical symptoms — understandably, since they’re the most visible. But a chronic illness can affect all aspects of life. The emotional, social, mental, and financial implications can be grueling for patients, too. As a patient diagnosed…
Have you seen the Apple TV+ series “Ted Lasso“? In it, Lasso is a fictional U.S. football coach who was recruited to manage a soccer club in the U.K. He was recruited because he knew nothing of European football. The club’s owner, Rebecca Welton, wanted the team to…
This column is my 100th for Pulmonary Fibrosis News. Thank you for allowing me to share my journey with you every week. I’ve been humbled by so many of you who feel comfortable sharing your stories with me and other readers. I’ve recently returned from the Pulmonary Fibrosis…
As patients, it’s crucial to know our bodies and the care they need. Understanding the complex ways that a chronic condition like pulmonary fibrosis may affect us over time, as well as the options available to treat and manage symptoms, is important for long-term quality of life.
