Karos Pharmaceuticals recently announced that its small molecule drug candidate, KAR5585, has advanced in Phase 1 clinical testing. The drug is being developed for the treatment of pulmonary arterial hypertension (PAH) and other diseases characterized by extensive fibrosis. KAR5585 received Orphan Drug designation for the treatment of PAH by the U.S. Food and Drug Administration…
Karos’ Experimental Therapy for PAH and Fibrotic Diseases, KAR5585, Advances in Phase 1 Study
In October 2015 – which was Healthy Lung Month – FOX 4 Now shared this video where you can see FOX 4 Morning Blend news reporter Michelle Cunningham and Dr. Imre Noth, an expert in lung disease, talk about what idiopathic pulmonary fibrosis means,…
City, a TV station from Toronto, Canada, shared this video in September 2015, where you can listen to NBA and Team Canada star, Nik Stauskas talk about idiopathic pulmonary fibrosis (IPF). Since September is IPF Awareness Month, this video was made as…
Japanese researchers reported that treatment with thrombomoduÂlin, an anti-clotting factor naturally produced in the body, reduced mortality in patients experiencing acute exacerbations of idiopathic pulmonary fibrosis (IPF). The findings also suggested that abnormal blood clotting may contribute to poor outcomes following these flares. ThrombomoduÂlin is a factor crucial for controlling the blood-clotting…
In this video shared by RBandH (Royal Brompton & Harefield NHS Foundation Trust, a leading specialist heart and lung centre based in London and Middlesex), you can learn how the Royal Brompton’s “interstitial lung disease unit played a central part in the reclassification of IPF and…
With this video from WWCIH Charity learn more about how a pulmonary function (breathing) test works, what its function is, and how your children can benefit from this test. This is a great video to show your children to help them understand what will…
There is currently no cure for pulmonary fibrosis and patients often face a prognosis of three to five years after diagnosis. However, medication and other treatment options can help improve patients’ quality of life. But as the disease evolves, there are some complications that…
The Canadian Pulmonary Fibrosis Foundation shared this video in 2015, where they show you some exercises that can help pulmonary fibrosis patients to improve their health and gain more muscle and respiratory strength. Watch the video to learn more about how you can…
Johns Hopkins School of Medicine researchers demonstrated that the smallpox vaccine may reverse established lung fibrosis in mice. The vaccine changed the reactivity of various types of immune T-cells, suggesting that balancing the actions of these immune players could be crucial in developing immunotherapeutic treatments for lung fibrosis. Scientists have known for some…
Clinical trials are needed for medical treatments to be approved by government organizations, such as the US Food and Drug Administration (FDA). Without clinical trials, doctors and other prescribing healthcare providers (such as nurse practitioners or physician’s assistants) cannot prescribe medications or recommend other medical treatments. If…
