Biopharmaceutical Bristol-Myers Squibb Company and the non-profit organization California Institute for Biomedical Research (Calibr) have established a worldwide research collaboration focused on the development of novel small molecule anti-fibrotic therapies, as well as an exclusive license agreement for the company to develop, manufacture and commercialize preclinical compounds from Calibr that result from the…
Bristol-Myers and Calibr Sign Collaboration for Anti-Fibrotic Therapy
A case study confirmed the need for a combined diagnosis approach in patients with pulmonary fibrosis and emphysema (CPFE) in contrast to a simplistic approach to lung function examination in symptomatic smokers. The study, entitled “Lung function testing in COPD: when everything is not so simple” was…
The Coalition for Pulmonary Fibrosis (CPF) recently published an overview of the most important 2014 developments regarding the research and treatment of pulmonary fibrosis (PF). The nonprofit organization, which was founded in 2001 with the purpose of accelerating research to find a cure for the disease, believes that…
A new study provides improved understanding of the challenges faced by people with Idiopathic Pulmonary Fibrosis (IPF) and their caregivers, which could help in the development of supportive care and could also improve quality of life in people afflicted with IPF. The study appeared December 23rd, 2014, in the…
Nanomaterials continue to gain in popularity in technological, biomedical, and many other applications, but their defining small size may pose a significant threat to lung health. Scientists have been concerned with the potential pulmonary toxicity of multi-walled carbon nanotubes (MWCNT) in the context of industrial settings, Back in October, Pulmonary…
A new study on Diffuse Parenchymal Lung Disease (DPLD) entitled “A case of pulmonary fibrosis associated with rheumatoid arthritis, scleroderma sine scleroderma and ANCA associated vasculitis” was published in SpringerPlus by Amritpal Singh Anand from Lakeland Rheumatology, St Joseph, USA, and colleagues. Diffuse parenchymal lung disease…
The prestigious Canadian Prix Galien award for Pharmaceutical Innovation for 2014 has been presented to InterMune Canada, a subsidiary of multinational drug firm Roche, for its Esbriet (pirfenidone) pharmaceutical medicine for treatment of idiopathic pulmonary fibrosis (IPF). Esbriet is currently the only Health Canada approved medication with a…
A new study entitled “Spectrum of diffuse parenchymal lung diseases with special reference to idiopathic pulmonary fibrosis and connective tissue disease: An eastern India experience” describes a prospective analysis performed in India to assess the burden of diffuse parenchymal lung diseases (DPLD), particularly two DPLD-causative disorders, idiopathic pulmonary…
Biotechnology company iBio Inc. recently provided updates at its Annual Meeting for shareholders and attendees on the development progress of IBIO-CFB03 and its potential to address unmet medical needs for the treatment of idiopathic pulmonary fibrosis (IPF) and other fibrotic diseases. The creator of IBIO-CFB03, Dr. Feghali-Bostwick from the Medical University…
Promedior, Inc. presented at the American Society of Hematology (ASH) meeting positive results from Stage 1 of its adaptive two-stage Phase 2 trial investigating PRM-151 use in patients with myelofibrosis. The treatment, a novel anti-fibrotic immunotherapeutic, yielded an overall response rate of 43% after 6 months of administration, which…
