Although multi walled carbon nanotubes (CNTs) are all the rage in product development, finding applications in sporting goods, electronic devices, and many other products, they pose a potential health hazard similar to asbestos. However, Dr. James Bonner, a professor at North Carolina State University, found a way to reduce…
Lung Injury from Carbon Nanotubes Reduced With Aluminum Coating
A case study of pulmonary fibrosis (PF) in association with autoimmune diseases, entitled “A case of pulmonary fibrosis associated with rheumatoid arthritis, scleroderma sine scleroderma and ANCA associated vasculitis” was published in SpringerPlus by Dr. Amritpal Singh Anand from Lakeland Rheumatology and colleagues in Michigan describing a rare…
A new study offering insights into pulmonary fibrosis, entitled “Secreted frizzled related proteins inhibit fibrosis in vitro but appear redundant in vivo” was published in Fibrogenesis &Tissue Repair by Dr. Rik JU Lories’ research group at University Hospitals Leuven in Belgium. In this new research, the authors investigated…
During the European Respiratory Society International Congress (ERS) 2014, held in Munich, Germany last month, a pre-specified subgroup analysis from the two replicate Phase III INPULSIS™ trials revealed that treatment with nintedanib retarded the decline in lung function in patients with idiopathic pulmonary fibrosis (IPF). The study’s findings were…
For the first time ever, a new European Patient Charter for patients who suffer from idiopathic pulmonary fibrosis (IPF) was developed by a group of advocates and presented to the European Parliament on September 30, during IPF World Week 2014. Biotechnology company InterMune, which is dedicated to research, development,…
Drug development company Promedior Inc. recently announced the results of its Phase 1B clinical trial of PRM-15 for treating Idiopathic Pulmonary Fibrosis (IPF). Their findings show that structural and functional imaging of IPF patients correlate with data obtained from standard pulmonary tests. The new data could lead to further development of the therapy as an…
Germany-based multinational pharmaceutical company Boehringer Ingelheim has launched a new mobile app and web page self-test as part of its efforts to raise awareness of Idiopathic pulmonary fibrosis (IPF), a chronic, progressive, severely debilitating, and ultimately lethal lung disease for which there are no FDA-approved treatment options in the U.S. Although…
The U.S. Food and Drug Administration (FDA) organized a workshop on pulmonary fibrosis, which took place on September 26th, in collaboration with the Coalition for Pulmonary Fibrosis (CPF), with the purpose of advocating for the disease throughout the country. Four of the eight panelists at the…
This month, Boehringer Ingelheim presented data concerning the use of nintedanib in patients with idiopathic pulmonary fibrosis (IPF) at the European Respiratory Society International Congress. Data covered two identical phase 3 trials: INPULSIS-1 and INPULSIS-2. “These results provide important insight on the effect of nintedanib across the patients studied…
FibroGen Inc. (FibroGen) recently presented complete data from a clinical study involving the experimental drug FG-3019 in patients with idiopathic pulmonary fibrosis (IPF.) A large group of patients treated with FG-3019 showed a decrease in lung fibrosis. The data was presented during the 18th International Colloquium on Lung and Airway Fibrosis (ICLAF) held in…
