8 Ongoing Research Projects for Pulmonary Fibrosis

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by Wendy Henderson |

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The world of science and medicine never stands still. Research constantly pushes things further along–creating, developing, and fine-tuning treatments so they are more effective, and working to establish why diseases happen and how they progress. Thankfully, pulmonary fibrosis research is also constantly moving forward. According to breathingmatters.co.uk, the Centre for Inflammation and Tissue Repair (CITR) at UCL Respiratory is working on several projects at the moment:

Investigating the development of scar tissue

Understanding why lung tissue becomes scarred will take scientists one step closer to coming up with ways to prevent it from happening or developing treatments to slow the progression or reverse the damage.

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Studying the effect of autoantibodies in pulmonary fibrosis

Understanding why and how the body creates autoantibodies which attack the blood vessels in patients with pulmonary fibrosis and other interstitial lung diseases and developing strategies to investigate these further.

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Improving molecular imaging 

Molecular imaging or PET scans allow doctors to see in detail any areas of fibrosis in the lungs. These scans help doctors to determine the best course of treatment.

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Investigating the activation of leukocytes

Scientists know that leukocytes (or white blood cells) become activated if a person has pulmonary fibrosis. Scientists are researching why this happens, if it can be reversed, and the role low oxygen concentration plays.

Idiopathic pulmonary fibrosis progression may depend on type of white blood cells.

Study of airway epithelial

Researchers are looking at the relationship between white cells and airway epithelium, comparing the white cells of pulmonary fibrosis patients to those of non-PF control patients.

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The INHALE study

Researchers are working to find out if some of the new drugs developed for the treatment of IPF can be used via inhalers and if inhaling the drugs would reduce side effects.

Aptuit and Chiesi Farmaceutici are partnering in a search for idiopathic pulmonary fibrosis treatments.

Study of platelets

Researching whether pulmonary fibrosis patients have stickier platelets than patients without any lung diseases and what role the platelets play in interstitial lung diseases.

The hormone found to decrease inflammation and fibrosis in a mouse model of idiopathic pulmonary fibrosis.

The Lung-COOL study

Developing the use of bronchoscopic cryoscopic lung biopsy as a minimally invasive tool for diagnosing idiopathic pulmonary fibrosis and other lung diseases.

Find out more about diagnostic tools used for pulmonary fibrosis.

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