IPF May Have Varied and Complex Genetic Roots

Genetic factors might drive at least part of the risk for idiopathic pulmonary fibrosis (IPF), particularly in familial forms of the disease, and a review from the Nanjing University School of Medicine, China, presented an updated view of genetic risk factors for IPF.

The article, “Candidate genes of idiopathic pulmonary fibrosis: current evidence and research,“ was published in the journal The Application of Clinical Genetics.

Familial IPF is thought to account for less than 5 percent of all IPF cases, but more recent estimates suggest that numbers are more likely approaching 20 percent. The only thing that differs between sporadic and familial IPF is that disease tend to appear earlier in the familial patients.

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