Pulmonary fibrosis (PF) is a respiratory condition that causes the formation of scar tissue in the lungs. It is progressive disease and can take years to progress. Because of thickening lung tissue, it is difficult for the lungs to properly transport oxygen to the bloodstream and organs, causing symptoms like shortness of breath or a dry and hacking cough.

PF is more common among middle-aged and older people, but it can develop in anyone.

Genetics may be a cause of pulmonary fibrosis, but in most cases, the cause is unknown — a condition known as idiopathic pulmonary fibrosis. Each patient tends to have a different experience with the disease, which can progress faster or slower depending on the patient.

There is currently no cure for pulmonary fibrosis. However, medication and other treatment options can help improve patients’ quality of life.

Medication to treat PF patients

  • Ofev (nintedanib)
  • Esbriet (pirfenidone)
  • Trisulfa-FPI (cotrimoxazole)

Investigational drugs for PF patients

  • AEOL 10150
  • FG-3019
  • GLPG1690
  • IBIO-CFB03
  • Lebrikizumab
  • PBI-4050
  • PRM-151
  • PTL-202
  • RES-529
  • Simtuzumab (GS-6624)
  • TD139
  • Tipelukast (MN-001)
  • Tralokinumab

Options for PF respiratory problems

Complementary PF treatments

  • Flu and pneumonia vaccines
  • Cough medicines or oral codeine
  • Vitamin D, calcium, and a bone-building medicine
  • Anti-reflux therapy

Note: Pulmonary Fibrosis News is strictly a news and information website about the disease. It does not provide medical advice, diagnosis or treatment. This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.