News

Context Partners with Research Institutions to Study Sigma1 Protein in Treatment of Fibrosis, Cancer

Context Therapeutics, a Philadelphia-based biotech, is collaborating with three leading institutions for research into the Sigma1 protein and its role in diseases. The institutions are Cedars-Sinai Medical Center, Fred Hutchinson Cancer Research Institute, and Fondation Synergie Lyon Cancer. The Sigma1 protein helps regulate the immune system and create stability…

Prometic to Advance IPF and Other Anti-fibrotic Therapies in Clinical Testing via Partnership in China

Prometic recently announced a financial agreement and partnership with Shenzhen Royal Asset Management (SRAM) to develop, manufacture, and commercialize several of its anti-fibrotic products in China, including PBI-4050 for idiopathic pulmonary fibrosis (IPF). PBI-4050 is an anti-fibrotic oral drug, which has demonstrated positive results in a Phase 2 study (NCT02538536) in patients…

Galapagos Therapy GLPG1690 Excels in Phase 2 IPF Trial, Spurring Further Development

GLPG1690, an investigational therapy developed by Galapagos to treat idiopathic pulmonary fibrosis (IPF), prevented further lung decline in a Phase 2a trial, allowing the Belgian pharmaceutical firm to rapidly move forward with the clinical development of this therapy. The trial, called FLORA (NCT02738801), involved randomly assigning 17 IPF patients treatment with GLPG1690 and…

Experts Will Gather at Inaugural IPF Summit in Boston Aug. 21-23

Key leaders in the idiopathic pulmonary fibrosis therapy development industry, representing large pharma and biotech firms, academia  and contract research organizations, will gather at the inaugural IPF Summit in Boston, Aug. 21-23. This forum will cover the latest in IPF drug development, from late discovery to early clinical studies.

FibroGen Shares Positive Results of Phase 2 Trial of Investigational Therapy Pamrevlumab

A Phase 2 trial testing the investigational therapy pamrevlumab (FG-3019) in patients with idiopathic pulmonary fibrosis (IPF) has shown positive and encouraging results, FibroGen, the drug’s developer, announced. In addition, combining pamrevlumab with the FDA-approved IPF therapies Esbriet (pirfenidone) and Ofev (nintedanib) was found to be safe. These results will be…

Three Lakes Partners Launches $1 Million ‘IPF Catalyst Challenge’ Competition

Three Lakes Partners, a venture philanthropy organization that finances research in idiopathic pulmonary fibrosis (IPF), has launched its $1 million IPF Catalyst Challenge — a competition to fund the most promising ideas in improving quality of life for IPF patients. The challenge is open to nonprofit groups as well as for-profit ventures. The…

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