Lung injuries caused during the progression of pulmonary fibrosis can lead to an increase in two inflammatory proteins, IL-6 and IL-33, which can trigger muscle damage and weight loss, a mouse study says. The study, “Elevation of IL-6 and IL-33 Levels in Serum Associated with Lung…
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Rosavin, an active compound found in the plant Rhodiola rosea, commonly known as golden root or Aaron’s rod, can prevent pulmonary fibrosis (PF) manifestations in mice, a study has found. This discovery, published in the journal Biomedicine & Pharmocotherapy, suggests that rosavin may be a promising candidate…
Contrary to what has been suggested, antacid therapies may not change survival or disease progression rates among people with idiopathic pulmonary fibrosis (IPF), an Australian study found. The study, “Gastroesophageal reflux and antacid therapy in IPF: analysis from the Australia IPF Registry,” was published in the journal…
Ofev (nintedanib) can prevent disease progression in people with idiopathic pulmonary fibrosis (IPF) regardless of their prognosis at treatment start as staged by the…
Exposure to cigarette smoking and lipopolysaccharides, components of the cell wall of certain bacteria, can lead to more severe lung fibrosis, a mouse study shows. The study, “Cigarette smoke exposure combined with lipopolysaccharides induced pulmonary fibrosis in mice,” was published in the journal Respiratory Physiology and Neurobiology.
A long-term collaboration was announced to accelerate the discovery of new medicines for idiopathic pulmonary fibrosis (IPF) and chronic kidney disease (CKD) by combining BenevolentAI’s expertise in artificial intelligence (AI) and machine learning with AstraZeneca’s pharmaceutical and clinical data. BenevolentAI, a U.K.-based company, developed an AI system…
Cumbersome security procedures, rising airfares, and shrinking legroom have made commercial air travel difficult enough these days — even for healthy passengers. Imagine how much harder it is for patients with rare diseases who must get to doctors’ appointments or clinical trials that are hundreds of miles away from home.
Pulmonary rehabilitation — a multidisciplinary intervention designed to manage the symptoms of different chronic lung diseases — may improve the exercise capacity and quality of life of patients with idiopathic pulmonary fibrosis (IPF) without generating any adverse events, a review study has found. The study, “Pulmonary…
Paragonix Technologies and the Lung Transplant Foundation (LTF) are expanding their collaboration to drive the development of several technologies aiming to improve donor lung preservation for transplant. These technologies include the Paragonix SherpaLung Preservation System, a special device designed to ensure lung preservation and viability during transport from…
Proliferation and inflammation of human lung fibroblasts is controlled by small RNA molecules called long non-coding RNAs, a study reports. The study, “Long intergenic non-coding RNAs regulate human lung fibroblast function: Implications for idiopathic pulmonary fibrosis,” was published in the journal Nature Scientific Reports. While the cause of…
