Preclinical Study Shows Anti-fibrotic Effects of Cancer Therapy for IPF Fibroblasts

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    Panobinostat, an approved treatment for multiple myeloma, exerts anti-fibrotic activity, inducing cell death and reducing the proliferation of lab-grown fibroblasts from idiopathic pulmonary fibrosis (IPF) patients, a preclinical study reports.

    The data also suggest that, despite an ability to inhibit cellular pathways involved in fibrosis, approved IPF therapy Esbriet (pirfenidone, marketed by Genentech) is not as effective as panobinostat in blocking the growth of IPF fibroblasts. Learn more here.

    Are you interested in updates on this research?

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