Research and Development
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Study Finds Infant Lung Disease Shares Tissue-Repair Issue With IPF
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Study Finds Infant Lung Disease Shares Tissue-Repair Issue With IPF
A lung-scarring disease that affects preterm infants has a tissue repair signaling problem seen in idiopathic pulmonary fibrosis, Vanderbilt University researchers report.
The discovery increases scientists’ understanding of the mechanisms underlying bronchopulmonary dysplasia and IPF. It also raises the possibility of treating both disorders by targeting the signaling dysfunction.
Researchers published the study in The American Journal of Pathology. The title is “A Shared Pattern of β-Catenin Activation in Bronchopulmonary Dysplasia and Idiopathic Pulmonary Fibrosis,”
Bronchopulmonary dysplasia and IPF occur on opposite sides of the human spectrum. Bronchopulmonary dysplasia stems from premature newborns’ long-term use of respiratory support, while IPF commonly develops in a person’s 60s or later.
Although they have different causes, growing evidence suggests they share common drivers of disease. One is problems with lung repair processes.
Read more about this study here: “IPF and Infant Lung Disease Share Tissue-Repair Problem, Study Finds“
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