Blocking an enzyme — called 15-PGDH — in a mouse model of pulmonary fibrosis (PF) limited early-stage inflammation and the development of fibrosis in the lungs, aiding the animals’ survival, a study demonstrated. These findings support further work targeting 15-PGDH as a…
Blocking 15-PGDH Enzyme Seen to Ease Inflammation, Fibrosis in Mouse Model
Have you ever suddenly realized you are part of something special? This happened to me today during a video call with other members of the Bionews Insights (BNI) team. BNI is a relatively new division of our company, Bionews, focused on market research. The team is small, but this…
Conditions affecting the heart, stomach, and esophagus occur more frequently in patients whose diagnosis of idiopathic pulmonary fibrosis (IPF) is delayed, coming more than one year after the onset of symptoms, according to a recent study. This delayed diagnosis seems, however, to have no impact on the risk of…
A three-year pulmonary rehabilitation program — a combination of aerobic, resistance, and breathing exercises — helped to maintain lung and muscle strength before a double-lung transplant in a middle-aged man with idiopathic pulmonary fibrosis (IPF) and a sedentary lifestyle, a case study reports. The study “Long-Term…
Biognosys and Boehringer Ingelheim are working together to expand the use of cutting-edge technologies for large-scale protein analysis in drug discovery, beginning with a study of potential new treatment approaches to idiopathic pulmonary fibrosis (IPF). Biognosys announced that it will bring its expertise in proteomics — the…
Exposure to secondhand smoke, dust, or asbestos in the workplace is linked to a significantly higher risk of developing idiopathic pulmonary fibrosis (IPF), according to findings of an Australian study. These results suggest that “the burden of IPF could be reduced by intensified tobacco control, occupational dust control measures…
Two weeks after my mom, Holly’s, double-lung transplant, she was discharged from the hospital. Although she was weak, she was walking, talking, eating, and, best of all, breathing on her own. After three months on a ventilator, the transplant brought her back to life.
The dry, persistent cough associated with idiopathic pulmonary fibrosis (IPF) is arguably the most difficult symptom of this life-threatening lung disease. Pulmonary fibrosis is defined simply as scarring in the lung, which always is progressive in patients with IPF. Unfortunately, there is nothing simple about this disease, and the scarring…
Failure of organs other than the lungs can be a predictor of mortality risk in people hospitalized due to acute exacerbations of idiopathic pulmonary fibrosis (IPF), a study reported. Elevated levels of C-reactive protein, a sign of inflammation, is also a risk factor for in-hospital mortality in these patients.
Scientists created an online cell atlas containing information on the gene activity of more than 300,000 lung cells taken from patients with idiopathic pulmonary fibrosis (IPF) and chronic obstructive pulmonary disease (COPD). The new atlas adds to the knowledge of the complex cellular and molecular mechanisms involved…
