Auto-immunity may have a role in the development of fibrotic idiopathic interstitial pneumonias (fIIP), a disease once thought to result solely from environmental factors. New research suggests a possible genetic link, associating two variants of the human leukocyte antigen (HLA) allele to an increased risk of fIIP. The study, “Genome-wide…
Salvianolic acid B, a compound isolated from red sage and a main component of the traditional Chinese medicine known as Yiqihuoxue formula, prevented fibrotic changes both in bleomycin-treated mice and in cell culture models. These findings indicate the compound may be worth exploring as a less toxic alternative to treating fibrosis. Traditional Chinese medicine is…
The name Robert Craig might not ring a bell, but the stage name Evel Knievel is universally recognized. Born Oct. 17, 1938, Evel Knievel grew up to be a famous motorcycle stunt performer and entertainer who dedicated his life to defying death. In fact, he became known not only for his…
https://www.youtube.com/watch?v=sz-iLi-B3Gg Pulmonary fibrosis is a lung disease that causes the scarring of the lungs, resulting in breathing difficulties. The condition can affect anyone, at any age, although the patients most at risk are usually older patients. Unfortunately, up until now there is still no cure for pulmonary fibrosis but there…
Merck is acquiring Afferent Pharmaceuticals — including its therapeutic candidates targeting the P2X3 receptor, now in clinical testing for neurogenic conditions that include chronic respiratory diseases — under a definitive agreement announced by the two companies. A lead investigational drug developed by Afferent, AF-219, is under evaluation in a Phase 2b dose-escalating study (…
1. Find Information About Pulmonary Fibrosis It’s normal for patients to be overwhelmed by a diagnosis of pulmonary fibrosis (PF). PF is a respiratory disease that causes scarring or fibrosis in the lung tissue, and in most cases the causes are not fully understood. Being a rare condition, it’s…
Pulmonary fibrosis is a disease in which tissue deep in your lungs becomes thick and stiff, or scarred, over time. Most of the time, the cause of how it develops is unknown and in these cases, it’s called idiopathic (unknown cause) pulmonary fibrosis. In this video, shared by the Institute…
A study from the Centre Hospitalier Universitaire de Liège at Sart Tilman recently reported that two growth factors, IGFBP-1 and IGFBP-2, are increased in the blood of untreated patients with idiopathic pulmonary fibrosis (IPF). People receiving treatment had lower IGFBP-2 levels that those who were not treated, indicating the factors might be…
Patients with idiopathic pulmonary fibrosis (IPF) often exhibit cardiovascular manifestations that affect patients’ morbidity and mortality according to the study”Cardiac manifestations of idiopathic pulmonary fibrosis,” published in Intractable and Rare Diseases Research. The authors reviewed evidence that links cardiovascular diseases to IPF and how the co-morbidities…
For people who live with idiopathic pulmonary fibrosis (IPF), traveling is not impossible, but it involves determined precautions and preparations. Traveling by plane can have respiratory implications so it is important that patients contact the airline beforehand to prevent any problems, as explained in this video by Professor Carlo Vancheri…
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