AdAlta, a biotech that develops protein-based therapeutics, has retained FujiFilm Diosynth Biotechnologies to manufacture AD-114, AdAlta’s lead drug molecule for the treatment of idiopathic pulmonary fibrosis (IPF). AdAlta is using its proprietary technology platform to create i-bodies, a new class of protein therapeutics that are the human equivalent of the antigen-binding domain…
It’s estimated that 5 million people worldwide have idiopathic pulmonary fibrosis (IPF). The life-threatening condition primarily affects the over-50 age group, although younger people are not immune. Idiopathic means that the cause of the disease is unknown, pulmonary means lungs, and fibrosis means scarring. Simply speaking — IPF is…
Patara Pharma recently presented positive Phase 2 data on its lead candidate, PA101, for the treatment of refractory chronic cough in patients with idiopathic pulmonary fibrosis (IPF). The findings were given at the recent European Respiratory Society International Congress in London. PA101 is a late-stage immune modulator with mast…
The European Commission (EC) has granted Galapagos’ investigational product GLPG1690 orphan drug designation for the treatment of patients with idiopathic pulmonary fibrosis (IPF). GLPG1690 is a selective autotaxin inhibitor that was demonstrated to have a favorable safety and tolerability profile in a Phase 1 study in healthy volunteers. Autotaxin plays an…
Relax the Easy Way Has anyone ever told you to “relax?” That probably didn’t work out very well for them. You probably tensed up at the remark. There’s something about those words — relax, be calm, and calm down — that trigger a deep emotional response. These ways to relax…
1. Knowing How Esbriet Works for Pulmonary Fibrosis May Help Improve Safety, Effectiveness Researchers are a step closer to understanding the molecular mechanism of action in Esbriet (pirfenidone), the anti-fibrotic drug used to treat pulmonary fibrosis. 2. Esbriet Found to Reduce Idiopathic Pulmonary Fibrosis Progression Across Disease Stages…
Hollywood legend Jerry Lewis recently gave an interview to CBS Sunday Morning host Tracy Smith where the multi-talented 90-year-old talked about his latest movie, his health, his charity work and reminisced about his long partnership with comedian, actor and singer Dean Martin. Read more about Jerry Lewis’…
According to the National Heart, Lung and Blood Institute, here are several less common symptoms and signs of idiopathic pulmonary fibrosis that you might develop over time. 1. Rapid and shallow breathing. Here are some simple facts about idiopathic pulmonary fibrosis. 2. Fatigue…
Long-term treatment of idiopathic pulmonary fibrosis (IPF) patients with Ofev (nintedanib) showed positive effects in keeping disease progression at bay, while inducing manageable side effects, Boehringer Ingelheim Pharmaceuticals announced. This finding comes from the INPULSIS-ON clinical trial — an extension study of the INPULSIS trial — designed to assess the long-term effects of…
Meet Gifted Organs, a pop band made up of transplant recipients and support musicians whose music celebrates the “Gift of Life” and increases awareness about the organ donation process. Read about how lung transplants gave two pulmonary fibrosis patients hope. “‘Gifted Organs’ hope to raise awareness, both in the UK and…
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