Global Blood Therapeutics has enrolled its first patient in the ZEPHYR Phase 2a clinical study assessing the safety and effectiveness of GBT440 in treating hypoxemia (low levels of oxygen in the blood) in patients with idiopathic pulmonary fibrosis (IPF) who are on supplemental oxygen at rest. GBT440 is an…
Global Blood’s Phase 2a Trial Underway to Treat Hypoxemia in IPF Patients
In this short video from Boehringer Ingelheim Idiopathic Pulmonary Fibrosis shared in September 2014, Professor Vincent Cottin from the National Reference Center for Rare Pulmonary Diseases in Lyon, France talks about how excessive coughing impacts the lives of patients with idiopathic pulmonary fibrosis (IPF). Discover six risk factors…
Blocking a particular pathway — called c-Jun N-terminal Kinase (JNK) — may reduce lung remodeling and fibrosis, researchers said in a multi-part study reporting the effects of a JNK inhibitor in a mouse model and, subsequently, in a clinical trial involving patients with idiopathic pulmonary fibrosis (IPF). The study, “JNK inhibition reduces lung…
Yesterday, Kim Fredrickson joined Pulmonary Fibrosis News and hosted a special Facebook Live about being a good friend to yourself while living with pulmonary fibrosis (PF). Read Kim’s full column about it here. “There are so many things we can’t control when you have PF,…
We just celebrated Thanksgiving in the United States, and I am feeling a lot of gratitude that I am still in the land of the living this holiday season. What a blessing each day and each breath is! Of course, keeping…
If the lung function in patients with chronic lung disease such as pulmonary fibrosis declines too much, they may need to undergo a lung transplant. In this amusing animated video from Alt Shift X shared in June 2013, we look at lung transplants and what role the…
As a typical Canadian winter commenced with vengeance this weekend, bringing blistery cold winds, snow and ice, I find myself both fearful and anxious about how my lungs will fare throughout these upcoming months. While I have never been someone who has loved winter, I do appreciate the…
Vitamin D is often called the “sunshine vitamin,” mostly because we get it naturally when the sun’s UV rays interact with our skin, which triggers the vitamin’s synthesis. The vitamin helps our body’s absorption of calcium to keep our bones strong and encourage healthy cells to grow. Last year, researchers demonstrated the protective effects of vitamin…
A higher fat-free mass index — a measure that takes a person’s muscle mass into account — predicts better survival in patients with pulmonary fibrosis, while body mass index (BMI) does not, according to a new study. Although researchers could not explain how body composition impacts disease progression, the findings may provide another…
Mindfulness seems to be the latest buzzword, with claims that adopting a more mindful approach to life can help with a myriad of ailments. But can it help patients with idiopathic pulmonary fibrosis? Find out about the five main factors for living well with pulmonary fibrosis. A new…
