News

Adults with idiopathic pulmonary fibrosis (IPF) who had greater diversity of mouth bacteria tended to have worse lung function and a higher risk of death than did those with a less diverse bacteria population in their mouths, a new large-scale study shows. Interestingly, however, those with a higher proportion…

Acute exacerbations, or sudden bouts of symptom worsening, increase the mortality risk after lung transplantation in people with interstitial lung diseases (ILDs), including idiopathic pulmonary fibrosis (IPF), a study reports. While a lung transplant is considered an effective treatment for ILDs, these findings “suggest that caution is required during decision-making,…

Sweden-based Vicore Pharma has granted exclusive rights to pharmaceutical company Nippon Shinyaku to develop and commercialize its treatment candidate C21 (VP01) in Japan, with an initial focus on idiopathic pulmonary fibrosis (IPF). Nippon will be operationally and financially responsible for the development of C21 in Japan, where…

Five new Pulmonary Fibrosis Foundation (PFF) scholars will each use $100,000, granted over the course of two years, to research new ways to diagnose, treat, or manage pulmonary fibrosis (PF). The six-year-old program awards grants each year to help scientists improve their understanding of PF, a chronic…

A Phase 2a clinical trial has finished testing the experimental therapy ENV-101 (taladegib) in people with idiopathic pulmonary fibrosis (IPF), according to its developer, Endeavor BioMedicines. Endeavor did not include in its announcement any specific data from the trial, but John Hood, PhD, the company’s co-founder, CEO, and…

Bersiporocin, an oral therapy for idiopathic pulmonary fibrosis (IPF) now being tested in a Phase 2 clinical trial, has been granted orphan drug status in Europe by the European Medicines Agency (EMA). The EMA gives this designation to treatments that have the potential to improve care for people with…

For the 14th year, a cast of Broadway luminaries will take the stage for the Pulmonary Fibrosis Foundation’s (PFF) largest fundraiser, Broadway Belts for PFF! The March 18 gala, which may also be viewed virtually, will raise funds and awareness for the more than 250,000 U.S. residents thought to…

The U.S. Food and Drug Administration (FDA) has approved Fibresolve, an AI or artificial intelligence-based software that’s designed to help — noninvasively — in the diagnosis of idiopathic pulmonary fibrosis (IPF) and other lung diseases marked by fibrosis, or scar tissue buildup. This marks the first FDA clearance of…

Almee, an investigational app that offers personalized treatment to help people with pulmonary fibrosis (PF), was found to significantly reduce anxiety levels in PF patients who participated in a pivotal randomized study. Positive results from the COMPANION (NCT05330312) study were announced by Alex Therapeutics and Vicore…

Berberine, a naturally occurring plant compound, eased the signs and symptoms of pulmonary fibrosis (PF) in a mouse model where the disease was triggered by exposing animals to fine particulate matter found in air pollution. The findings “offer novel insights into the mechanisms underlying the beneficial effects of…