Simultaneous inhibition of two signaling pathways mediated by TGF-beta1 and periostin can halt progression of idiopathic pulmonary fibrosis in mice, a new study reveals. The study, “The Cross-Talk Between TGF-β and Periostin Can Be Targeted for Pulmonary Fibrosis,” was published in…
Simultaneous Inhibition of TGF-beta1, Periostin Signals Can Halt PF Progression in Mice, Study Shows
Nitric oxide, a gas that induces the relaxation and widening of lung airways, has received orphan drug designation by the U.S. Food and Drug Administration (FDA) for the treatment of idiopathic pulmonary fibrosis (IPF). The gas will be delivered in pulses through Bellerophon Therapeutics’ patented…
Patients living with a chronic illness must learn quickly to manage their medication. Access to the right treatment can be a matter of life or death, especially when talking about a rescue inhaler in response to a respiratory crisis. I’ve experienced one respiratory crisis since being diagnosed with…
Genetic screening that can identify variants of the mucin-causing MUC5B gene — the key risk factor that predisposes people for idiopathic pulmonary fibrosis (IPF) — may hold the key to the development and administration of targeted therapies that may prevent the disease before it can progress…
Last week, I wrote about the benefits of having multiple caregivers during my mom’s recovery from a double-lung transplant. My dad, Aunt Shari, and I shared the responsibilities so that Mom had the best care from each of us. Preventing caregiver burnout and having someone else who…
A large number of people with pulmonary fibrosis (PF) were unaware this disease even existed before they were diagnosed. I was diagnosed with idiopathic pulmonary fibrosis (IPF) in December 2014 and received a lung transplant a year later. Doctors speculated that I had been living with IPF…
I want to increase awareness about the impact on those of us with lung disease when people smoke in public places. Since being diagnosed with idiopathic pulmonary fibrosis (IPF), I’ve twice inhaled secondhand smoke at the entrance of a grocery store. One of those times, I was rushed to…
Surgery is the most effective option to treat lung cancer in people with less severe idiopathic pulmonary fibrosis (IPF), a Korean study has found. For IPF patients who have a poorer prognosis (more advanced GAP stages), researchers recommend accounting for cancer clinical stage and estimated tolerability…
Esbriet (pirfenidone) shows similar benefits for people with idiopathic pulmonary fibrosis (IPF) in real-world settings as it does in clinical trials, a new study shows. “Pirfenidone in real life: A retrospective observational multicentre study in Italian patients with idiopathic pulmonary fibrosis” was published in the journal…
I feel vulnerable writing about this topic, but if this column opens the door for conversation, my discomfort will be worth it. I recently had a conversation with one of my colleagues about having kids. She is healthy, but I am living with a terminal lung disease called idiopathic pulmonary…
