High Levels of Vimentin Protein Linked to Lung Fibrosis, Study Shows

High levels of the protein vimentin in the lung tissue of patients with idiopathic pulmonary fibrosis (IPF) contribute to disease progression, an early study’s results show. Inhibiting vimentin can prevent fibroblasts — the cells responsible for the production and buildup of scar tissue (fibrosis) — from invading the lungs and producing…

Several months after my lung transplant in 2015, my transplant team OK’d me to travel by air. My wife and I were in the doctor’s office and gave each other a grin. We knew then that we could go back to our special place: Maui. After careful consideration, we decided not…

Blood levels of immune cells called monocytes may help predict disease severity and determine the risk of poor outcomes in patients with idiopathic pulmonary fibrosis (IPF) and other fibrotic diseases, a retrospective study suggests. The study, “Increased monocyte count as a cellular biomarker for poor outcomes in fibrotic diseases:…

Although patients with idiopathic pulmonary fibrosis (IPF) who take Ofev (nintedanib) or Esbriet (pirfenidone) have similar clinical outcomes, adherence to treatment is higher among those who have secondary insurance coverage, especially from charitable organizations, a study finds. The study, “Retrospective Analysis of Medication Utilization and Clinical Outcomes in…

It is inevitable as we grow and develop throughout the years that our priorities will change. Throughout the last decade, which I believe is considered “young adulthood” for me, I have adapted mine seemingly hundreds of times. The greatest adjustment, however, came with my diagnosis of idiopathic pulmonary…

Envisia Genomic Classifier — a non-invasive diagnostic test developed by Veracyte and used as a complement to high-resolution computed tomography (HRCT) imaging — improves diagnosis of interstitial lung disease (ILD) and idiopathic pulmonary fibrosis (IPF) compared with HRCT alone, according to a recent study. The findings were published…

In my career, I am privileged to offer children and families support in some of their most vulnerable moments. These include times when children are experiencing bullying, trauma, or grief. When a child is being bullied because they are different, their parents and caregivers regularly make the comment,…

After contracting respiratory syncytial virus (RSV) and having an exacerbation of my idiopathic pulmonary fibrosis, I was homebound. I wasn’t able to walk more than 15 feet and was having some anxiety. The majority of my anxiety issues pertained to coughing episodes. When I stood up from sitting, my…

Quantification of so-called honeycombing areas (patches of cystic spaces) in the lungs seen through high-resolution computed tomography (HRCT) may be a predictor of mortality in people with idiopathic pulmonary fibrosis (IPF), according to a retrospective analysis. The study, “Quantitative CT analysis of honeycombing area predicts mortality in…

The quality of life of people with idiopathic pulmonary fibrosis (IPF) is strongly associated with clinical changes in lung function, comorbidities, disease duration, and overall clinical course of the disease, a study shows. The study, “The clinical course of idiopathic pulmonary fibrosis and its association to quality…