Fibrosis-targeted Therapies Will Be Focus of Start-up Based on Discovery at Singapore Lab

Fibrosis-targeted Therapies Will Be Focus of Start-up Based on Discovery at Singapore Lab

Research into key drivers of fibrosis will be used by a Singapore-funded biotechnology start-up, Enleofen Bio, to possibly develop first-in-class therapeutics for pulmonary fibrosis (PF) and other fibrosis-related diseases. The intellectual property that came from the work performed at two Singapore institutions, Duke-NUS Medical School (Duke-NUS) and National Heart Centre…

British Lung Foundation Funds 3 Research Projects on Personalized Medicine for IPF, Other Lung Diseases

The British Lung Foundation (BLF), in collaboration with GlaxoSmithKline (GSK) has awarded £1.3 million (about $1.68 million) in grants to three lung disease experts to support research projects on finding new therapeutic targets for personalized medicine in idiopathic pulmonary fibrosis (IPF), bronchiectasis and chronic obstructive pulmonary disease (COPD). “Our professorships…

Learning to Adjust As PF Worsens

Adjust, adjust, adjust… Part of living with pulmonary fibrosis is adjusting to changes that happen as our disease worsens. There is so much to adjust to that it can be overwhelming at times. Supplemental oxygen I first started using supplemental oxygen two months after I received my diagnosis.

6 Tips for Protecting Your Lungs

We only get one set of lungs so it’s imperative that we look after them. This is even more important when it comes to diseases that directly affect the lungs, as keeping lungs healthy can help slow down the progression of the disease and ease the symptoms. To help you take the best…

Watching Others Leave for Vacation

I have always enjoyed traveling and have been privileged enough as a young adult to enjoy vacations that span the globe. While some were related with business, such as being flown to Calgary, Saskatchewan, Halifax, New York City, Dubai, Colorado, California and Washington, others were purely for leisure. If you…

Review Study Summarizes Nutritional Goals for IPF Patients

Doctors increasingly recognize nutrition as a key factor in improving overall function, exercise tolerance and quality of life in patients with pulmonary fibrosis and other lung diseases. With that in mind, a team has reviewed current literature and summarized nutritional goals for lung disease patients. The review titled “Nutrition…

Potential Therapy for IPF, PAT-1251, Seen To Be Safe and Well-Tolerated in Phase 1 Trial

A first clinical trial of the safety and tolerability of a potential treatment for idiopathic pulmonary fibrosis (IPF) and other fibrotic diseases —  PAT-1251, being developed by PharmAkea — was successfully completed in healthy volunteers, the company announced. PAT-1251 is an investigational small-molecule designed to specifically inhibit the LOXL2 enzyme. Patients with fibrotic illnesses,…