1. Medication Currently, two medicines are approved by the U.S. Food and Drug Administration (FDA) for patients with idiopathic pulmonary fibrosis (IPF). Both Esbriet (pirfenidone) and Ofev (nintedanib) became available in 2014. Taken orally, Esbiret is an anti-inflammatory and an anti-fibrotic drug shown effective in reducing inflammation and fibrosis simultaneously.
Afferent Pharmaceuticals announced the results from the first cohort of a two-cohort Phase 2b study, revealing that the company’s AF-219, an orally available antagonist of the P2X3 receptors, significantly reduced cough frequency in patients with chronic cough, a commonly experienced symptom in people with idiopathic pulmonary fibrosis (IPF). P2X3 receptors are activated…
Breathing is the process that moves air in and out of the lungs, or oxygen through other respiratory organs. This is one of the most important things that our body does, that allow us to be alive. Pulmonary fibrosis patients have difficulties in breathing, which means that something in their bodies…
https://www.youtube.com/watch?v=JcZuUt8jXBI The average survival of patients with idiopathic pulmonary fibrosis (IPF) is between three and five years after diagnosis, and only 20% of them survive past this time. Like many others, Anita Hatfield struggled for three years with the disease and died last March from complications related to idiopathic pulmonary fibrosis.
New analyses, presented at the American Thoracic Society (ATS) 2016 Annual Conference, further support the efficacy and safety of nintedanib (Ofev) in treating idiopathic pulmonary fibrosis (IPF). Boehringer Ingelheim shared a host of data at the meeting, establishing nintedanib as an important player in IPF management, irrespective of disease severity. “IPF…
Renate Huebner was diagnosed with pulmonary fibrosis at the age of 65 in August 2012. With 10 children and 38 grandchildren, Renate’s large family didn’t quite understand the disease at first. Now, after her death a year ago, the family is focused on the project Give Air and continuing the matriarch’s…
https://www.youtube.com/watch?v=tnjwJTTVmKs&feature=youtu.be Living with a chronic illness means that not all days are good days. Sometimes you wake up feeling unwell but still have to get on and do things, leave your house and face the day. To help you through those rough days, Lauren from …
https://www.youtube.com/watch?v=sB71s2_klbA I Am News, a local community news project from Swansea, UK, shared this video where you can meet Margaret Marsh. Margaret is an idiopathic pulmonary fibrosis patient, a member of the British Lung Foundation and Chair of Chepstow Breathe Easy Group. In this video, she…
While living with a serious rare lung condition such as pulmonary fibrosis, it is understandable that several doubts and questions about it may come up. In this video, shared by Demystifying Medicine, learn more about some important questions regarding pulmonary fibrosis. Is PF the…
Netrin-1, a factor produced by the extracellular matrix, drives the production and accumulation of fibrocytes, a fibrosis-promoting cell type in patients with systemic sclerosis (SSc)-induced pulmonary fibrosis, according to a study by Yale University School of Medicine researchers. Fibrocytes are cells that often reside in the extracellular matrix —…
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