News

Algernon Pharmaceuticals has begun screening patients for its Phase 2 clinical trial investigating its repurposed compound NP-120 (ifenprodil) for the treatment of idiopathic pulmonary fibrosis (IPF) and associated chronic cough. The study (NCT04318704) will be conducted at three sites in Australia and two in New Zealand, all…

The protective tips of chromosomes, called telomeres, are shorter in men with idiopathic pulmonary fibrosis (IPF) than age-matched peers, and these changes seem to be linked to lower blood levels of the male hormone testosterone, a study reported. Further…

Rates of hospitalization and in-hospital mortality dropped significantly for people with idiopathic pulmonary fibrosis (IPF) in the U.S. between 2006 and 2016, and hospitalizations were most common in colder months, an analyses of disease trends found. The study, “Trends and…

Single lung transplant patients with idiopathic pulmonary fibrosis (IPF) have a higher risk of developing lung cancer, according to a recent study — and these cancers are more likely to be diagnosed at an advanced stage and carry a worse prognosis. Thus, the researchers recommend prioritizing people with IPF…

A cell therapy approach based on transplanting a type of lung cells called type II alveolar cells halted scarring (fibrosis) in a rat model of idiopathic pulmonary fibrosis (IPF) with established disease. This anti-fibrotic effect was associated with a drop in lung levels of several fibrotic markers, the researchers said.

Treating acute exacerbations with the protein thrombomodulin (ART-123) in idiopathic pulmonary fibrosis (IPF) patients may be associated with short-term survival benefits, a review analysis reports. However, larger studies are needed to confirm these findings, the researchers noted. The study, “Efficacy…

New preclinical data support MRG-229, an investigative next-generation treatment for idiopathic pulmonary fibrosis (IPF), as safe and effective, miRagen reported. “We believe this body of evidence supports further development of MRG-229 as a potentially differentiated approach for the treatment of IPF,” William S. Marshall, PhD, the company’s president and CEO, said in…

Former New York Yankees center fielder and Latin Grammy nominee Bernie Williams is helping to raise awareness of idiopathic pulmonary fibrosis (IPF), the disease took his father’s life, as part of Boehringer Ingelheim’s national Breathless Ballad Challenge. The campaign aims to educate and empower people who have, or suspect…

Pulmonary fibrosis (PF) that results from inhaling silica dust is rebounding in wealthier counties after years of decline, due to a  rising demand for artificial stone in home construction and renovation, a study from Spain reports. The study traces the disease in a group of people who worked with…

Low levels of a protein called esRAGE, present in the blood and lungs of people with idiopathic pulmonary fibrosis (IPF), are associated with a poorer prognosis and lower survival rates, a study shows. These findings suggest that esRAGE may be related…