Potential IPF Treatment Limits Weight Loss, Lung Scarring in Mouse Model

Nogra Pharma’s experimental therapy GED-0507 limited body weight loss and the extension of lung scarring (fibrosis) — to a similar or greater extent than two approved anti-fibrotic therapies used as comparators — in mice with induced pulmonary fibrosis (PF), a study reported. These findings suggest that GED-0507 may be a therapeutic option for…

April is Donate Life Month. I have struggled to think of something new to say about organ donation. Everything I’ve written for Pulmonary Fibrosis News has been inspired by, or is in response to, organ donation. I’ve talked about both pre- and post-transplant challenges, caregiver struggles, grief, celebration, and…

When I was growing up, my mom used to say, “Charlene, there is something to be said about routine!” Usually she was referring to my sleeping habits: I would stay up far too late and then be tired the next day. She always told me that if I got into…

COVID-19 has been reported to cause lung fibrosis in some people, but the type of fibrosis that develops is distinct from what generally occurs in those with interstitial lung disease (ILD), according to a press release issued by the Pulmonary Fibrosis Foundation (PFF). COVID-19 (coronavirus disease 2019)…

People with pulmonary fibrosis (PF) and other chronic lung disorders should strictly limit social contact during the global spread of the respiratory illness COVID-19, a pulmonary expert said. Rahat Hussain, MD, a pulmonologist and assistant professor of internal medicine at the University of Texas (UT) Health Science Center…

Living through a pandemic means that people around the world are having new and uncomfortable experiences. Many, including me, are afraid. We fear for our health and for our loved ones. We fear for our economy, finances, businesses, and futures. I don’t want to diminish or ignore those fears, but…

A class of molecules called matrix metalloproteinases (MMPs) and tissue metalloproteinase inhibitors (TIMPs) show promise as biomarkers of the presence of idiopathic pulmonary fibrosis (IPF), according to a new study. MMPs and TIMPs are present at elevated levels in the bloodstream of IPF patients, and…

The news of organ transplants being paused at several medical centers around the world amid the COVID-19 pandemic is deeply troubling. As a patient living with idiopathic pulmonary fibrosis (IPF), I’m concerned, because ultimately, a lung transplant will be the only thing to save my life. I also…