Pliant Therapeutics announced that its lead therapy candidate PLN-74809 was designated an orphan drug by the U.S. Food and Drug Administration (FDA), an act that helps to advance its development as a possible treatment of…
FDA Names PLN-74809, Potential IPF Treatment, Orphan Drug to Speed Its Development
Being diagnosed with pulmonary fibrosis is not for the faint of heart. It is a rough road full of fears, losses, and unknowns. It’s difficult getting used to all that comes with this diagnosis, including lots of up and downs, tears, disbelief, and attempts to adjust. Taking good care…
Adding Ofev (nintedanib) to Esbriet (pirfenidone) for idiopathic pulmonary fibrosis (IPF) is tolerated by most patients and has a similar safety profile as taking each medication alone,…
The presence of swollen lymph nodes in patients with idiopathic pulmonary fibrosis (IPF) at the time of their diagnosis can be a predictor of poor prognosis, associated with stronger disease severity and lower survival, a study suggests.
Do NOX enzymes play a pivotal role in idiopathic pulmonary fibrosis (IPF)? This is the question researchers hope to answer with a newly funded research program evaluating the role of NOX enzymes. Genkyotex, a company focused on developing therapies for chronic diseases, recently announced that the U.S. National Institutes of…
Editor’s note: A continuation of Charlene Marshall’s monthly “Gratitude Miniseries.” Similar to my “Gratitude Miniseries” column for April, July was not one of my favorite months this year. While some good things happened, which I will highlight below, I had to navigate many social and emotional challenges…
The Pulmonary Fibrosis Foundation (PFF) has completed the enrollment of PF patients in its PFF Patient Registry, with the admission of the 2,002nd patient. Launched in 2016, the PFF Patient Registry was created to compile large quantities of data collected from anonymous PF patients, and use it to help…
About three months ago, I bought a used treadmill and started exercising at home. I used to go to pulmonary rehab three times a week. As my disease has progressed, going to pulmonary rehab has become too tiring for me. Just getting there and back as well as…
A mechanism triggered by the activation of two specific proteins called JAK2 and STAT3 was found to contribute to the damaging cellular transformations that occur in idiopathic pulmonary fibrosis (IPF), a study reports. Blocking this signaling pathway reduced the levels of lung damage in a rat model of IPF,…
Following a diagnosis of a life-threatening illness like idiopathic pulmonary fibrosis (IPF), days filled with happiness and gratitude can rare. After my own IPF diagnosis in early 2016, I had many days of confusion, anger, and fear of what my life as a young adult would look…
