Higher levels and activity of an enzyme, called urokinase plasminogen activator (uPA), were associated with fibrosis in lung tissue of patients with idiopathic pulmonary fibrosis (IPF). This suggests that uPA may be a target in treating lung fibrosis. The study, “The fibrogenic actions of lung fibroblast-derived urokinase: a potential drug target…
Enzyme Found in Urine and Blood Linked to Fibrosis in IPF Study
https://vimeo.com/105996688 Idiopathic pulmonary fibrosis (IPF) is a rare progressive lung disease with no known cause. Although there are medications and therapies that can treat the symptoms of the disease and help slow down its progression, there is no cure. Find out more about how pulmonary fibrosis is treated. In…
A lung fibrosis treatment based on a shark antibody is on the verge of entering a first clinical trial in patients. The treatment has shown promise in animal models of fibrosis, and offers hope for a therapy that is superior to current treatment approaches for lung fibrosis. Developed by Australian-based AdAlta, the compound is a…
The British Lung Foundation has a series of videos featuring idiopathic pulmonary fibrosis (IPF) patients sharing their stories. The patients come from all walks of life and their journeys are all very different. In this video, Joyce explains that it took four years before she received her idiopathic pulmonary fibrosis diagnosis.
People with idiopathic pulmonary fibrosis, and their caregivers, can learn more about this disease and its care using a free and online interactive program developed by ProPatient, the Pulmonary Fibrosis Foundation (PFF), and the Academy for Continued Healthcare Learning (ACHL). Called “Idiopathic Pulmonary Fibrosis: Partnering with Your Doctor,” the educational program offers…
https://vimeo.com/194483794 It’s estimated that 132,000 Americans are living with idiopathic pulmonary fibrosis, yet very few people are aware of the disease. Idiopathic pulmonary fibrosis (IPF) can be an extremely difficult disease to diagnose, mostly because the main symptoms can be attributed to many other diseases. Here are nine steps to help…
By developing a drug that blocks a molecule — going under the curious name, porcupine — Redx Pharma hopes to develop a new kind of treatment for idiopathic pulmonary fibrosis. The company’s porcupine program also aims to come up with drugs that can improve responses to cancer immunotherapy. “We’re…
https://vimeo.com/157197415 In this video from CME Corner shared in 2016, Dr. Steven Nathan is joined by two prominent pulmonologists, Dr. Marilyn Glassberg and Dr. David Lederer, to participate in a roundtable discussion about the progress against idiopathic pulmonary fibrosis (IPF). Find out about eight ongoing research projects for…
I’ll be honest, I’m not sure I have a good answer to this question, but I’ll share my journey delivering this message. My journey actually began by telling others I had breast cancer three-and-a-half years ago. Only 10 days elapsed between that awful phone call and my surgery. I…
When you think of someone who has a lung disease, such as idiopathic pulmonary fibrosis (IPF), it is easy to understand that physical exhaustion is likely a primary side effect. What may not be so easy to understand, however, is the mental exhaustion that comes with having…
