Black Tea Extract Reduced Fibrotic Features in PF Mouse Model

Black Tea Extract Reduced Fibrotic Features in PF Mouse Model

Feeding black tea extract to mice in models of pulmonary fibrosis (PF) lessened several disease-associated fibrotic markers, a recent study found. The results suggest black tea extract may have a beneficial therapeutic effect by reducing fibrotic features. The study “Anti-fibrotic effect of black tea (Camellia sinensis) extract in experimental…

PU.1 Inhibition May Help Treat PF, Other Fibrotic Disorders

A protein called PU.1 plays a central role in the deposition of connective tissue during fibrosis, according to new research. The findings also suggested that blocking PU.1 may be a therapeutic strategy for pulmonary fibrosis and other fibrotic disorders. The study, “PU.1 controls fibroblast polarization and…

Options for Care When IPF Makes Me Feel Unwell

It’s cold and flu season, and unfortunately, people with idiopathic pulmonary fibrosis (IPF) and compromised immune systems are bound to get sick. Despite our best efforts, it is likely that we’ll end up with the flu, a cold, or a more serious respiratory illness such as pneumonia. It…

Galapagos Expands Fibrosis Program with Evotec Partnership

Evotec and Galapagos will work together to develop a strategy to target fibrosis affecting several organs, the companies announced. The collaboration will focus on the development of small molecules designed to specifically target a new fibrosis biomarker identified and validated with Evotec’s proprietary platforms for fibrotic diseases…