Even before I received my official diagnosis of idiopathic pulmonary fibrosis (IPF), the thought of death consumed me. I had trouble sleeping. I would lie awake at night for several hours tossing and turning before finally falling asleep. The restlessness was a symptom of the IPF; the thoughts of…
Following My Diagnosis, Negative Thoughts Consumed Me
Indalo Therapeutics has launched a Phase 1 clinical trial testing the company’s lead antifibrotic candidate IDL-2965 for patients with fibrotic diseases such as idiopathic pulmonary fibrosis (IPF) and nonalcoholic steatohepatitis (NASH), an inflammatory liver disease. The biopharmaceutical company announced it has now dosed the first healthy volunteer in the…
Many patients with idiopathic pulmonary fibrosis (IPF) who are switching from Esbriet (pirfenidone) to Ofev (nintedanib) discontinue treatment, especially if they are underweight or have anorexia while being treated with Esbriet, a Japanese study says. The findings, “Negative impact of anorexia and weight loss during prior pirfenidone…
The pulmonary fibrosis (PF) community is invited to attend the Pulmonary Fibrosis Foundation‘s PFF Summit, which is the largest healthcare meeting on PF, offering data on the latest research. Attendees will get the chance to learn more about the potential of DNA sequencing and targeted therapies to…
We learn the most important lessons in the most difficult times, and I’m grateful to have had opportunities to live those lessons and share them with others. An internet search of popular life lessons showed me the following: It’s not all about you. Your health is your most…
Rare variants in genes that regulate the end regions of chromosomes — called telomeres — are linked with worse survival rates after lung transplant in pulmonary fibrosis (PF) patients, a study suggests. The study, “Lung Transplant Outcomes in Pulmonary Fibrosis Patients with Telomere-Related Gene Variants” was published in the…
Before receiving my official diagnosis of idiopathic pulmonary fibrosis (IPF), I was confident in my knowledge of it. Since it was suggested as a potential diagnosis, I spent many hours researching all facets of the disease. I was amazed by how many people were affected by IPF, yet so…
Treatment with Ofev (nintedanib) can significantly extend the survival of patients with idiopathic pulmonary fibrosis (IPF), an analysis of pooled data from six clinical trials shows. The analyis, conducted by an international research team, was published in the journal BMJ Open Respiratory Research, in an article titled “…
The American Thoracic Society (ATS) Foundation and Boehringer Ingelheim have awarded a physician scientist at Northwestern University this year’s research grant in idiopathic pulmonary fibrosis (IPF). Paul Andrew Reyfman, MD, was the recipient of the $100,000 fellowship, which will help fund his project, “Single Cell Transcriptomic…
Myth 1: If you can’t run with the big dogs, stay on the porch. Truth: In the words of the late great Dr. Martin Luther King Jr., “if you can’t fly then run, if you can’t run then walk, if you can’t walk then crawl, but whatever you do you…
