High levels of PD-L1 protein were found in the most aggressive fibroblasts that drive idiopathic pulmonary fibrosis (IPF) progression, making the protein — whose levels are increased in cancer cells to shield a tumor from the immune system — a potential new therapeutic target, a study suggests. The study, “…
Protein that Drives Cancer Is Potential New Therapeutic Target for Idiopathic Pulmonary Fibrosis, Study Suggests
This year’s edition of Broadway Belts For PFF! — a benefit event for the Pulmonary Fibrosis Foundation (PFF) — raised a record $400,000 to help fund pulmonary fibrosis (PF) research and patient programs. The evening of music, comedy, and performances at New York’s Edison Ballroom was hosted by Broadway…
Following the diagnosis of a life-threatening illness, it is hard to put into words the gamut of emotions a patient might feel. This is true at the time of diagnosis and throughout the disease progression, as emotions ebb and flow while patients learn to cope. At…
I have been a season ticket holder with the Cleveland Browns football team since it returned to action in the city in 1999 after a hiatus. I am part of a group of 11 men that holds seven seats. We passionately believe in our sports franchise. I felt the urge…
Saracatinib (AZD0530), an investigational oral therapy under development by AstraZeneca, was granted Orphan Drug Designation as a potential treatment for idiopathic pulmonary fibrosis (IPF) by the U.S. Food and Drug…
Exposure to dust in the aftermath of the World Trade Center attacks increased the risk of pulmonary fibrosis (PF) among responders, according to an evaluation of self-reported surveys. Researchers found that higher levels of dust exposure were associated with increased PF incidence. The study, “Pulmonary Fibrosis among World Trade…
I believe that people enter our lives when we need them most. I have always made friends easily, and I make an effort to grow and sustain these relationships. I value my connections and strive to nurture them. I have friendships with people I met while traveling and…
Exposure to silica dust may trigger pulmonary fibrosis (PF) because silica particles block a self-cleansing process used by cells, termed autophagy, which drives cell death in the lungs, a study using both human cells and mice showed. Researchers say the findings may improve…
“The whole is greater than the sum of its parts.” — Aristotle In today’s healthcare environment, an overwhelming percentage of resources are spent on treating diseases and their associated manifestations. While treatment of disease is an essential part of wellness, there is far more to being healthy than simply not being…
Increased levels of the signaling molecule IFN-gamma in the blood, as well as of other pro-inflammatory proteins and immune-response activators, can contribute to the worsening of acute symptoms in patients with idiopathic pulmonary fibrosis (IPF), a study finds. Therefore, assessment of these particular molecules may help predict IPF acute…
