Black Tea Extract Reduced Fibrotic Features in PF Mouse Model

Feeding black tea extract to mice in models of pulmonary fibrosis (PF) lessened several disease-associated fibrotic markers, a recent study found. The results suggest black tea extract may have a beneficial therapeutic effect by reducing fibrotic features. The study “Anti-fibrotic effect of black tea (Camellia sinensis) extract in experimental…

Any patient living with a chronic illness is familiar with the topic of self-care. It’s something that many of our medical team members, especially the allied healthcare professionals, talk to us about. But practicing self-care is not always as easy as it sounds. It has taken me nearly…

At 12:06 a.m. on Dec. 3, 2015, the much-anticipated phone call came. I knew what the call pertained to as soon as I saw the first digits on the phone’s screen. The caller identified himself as a nurse coordinator from Cleveland Clinic’s Transplant Center and then handed the phone over…

A protein called PU.1 plays a central role in the deposition of connective tissue during fibrosis, according to new research. The findings also suggested that blocking PU.1 may be a therapeutic strategy for pulmonary fibrosis and other fibrotic disorders. The study, “PU.1 controls fibroblast polarization and…

It’s cold and flu season, and unfortunately, people with idiopathic pulmonary fibrosis (IPF) and compromised immune systems are bound to get sick. Despite our best efforts, it is likely that we’ll end up with the flu, a cold, or a more serious respiratory illness such as pneumonia. It…

Evotec and Galapagos will work together to develop a strategy to target fibrosis affecting several organs, the companies announced. The collaboration will focus on the development of small molecules designed to specifically target a new fibrosis biomarker identified and validated with Evotec’s proprietary platforms for fibrotic diseases…

Canada’s SQI Diagnostics and the University Health Network (UHN) will work together to advance the development and approval of new rapid protein assays and a point-of-care (POC) diagnostic device to help surgeons assess the viability of lungs and other organs for transplant. This could represent an important step…