Treatment with Esbriet (pirfenidone, Genentech) or Ofev (nintedanib, Boehringer Ingelheim), or with steroids was found to be safe for idiopathic pulmonary fibrosis (IPF) patients needing a bilateral lung transplant (BLTx), a study reports. The research, “Effect of Antifibrotics on Short-Term Outcome after Bilateral Lung…
Esbriet and Ofev Use Prior to Lung Transplant Seen as Safe for IPF Patients in Study
The FOXM1 gene is a driver of lung fibroblast proliferation and activation in idiopathic pulmonary fibrosis (IPF), a new study shows. The findings highlight the therapeutic potential of targeting FOXM1 for pulmonary fibrosis treatment. The study “FOXM1 is a critical driver of lung fibroblast activation and fibrogenesis” was published in…
For as long as I can remember, I have always been passionate about traveling. While this has become more difficult since my idiopathic pulmonary fibrosis (IPF) diagnosis, I am grateful that it is not impossible. Having to pull an oxygen concentrator behind me wherever I go was not…
Like many of those living with serious chronic diseases such as idiopathic pulmonary fibrosis (IPF), Marj Korn depends on nurses to help her through the difficult journey. “They have always been kind and made sure to make me as comfortable as possible,” said the former senior recruitment manager. “I need…
The University of Virginia recently launched the Fibrosis Initiative, a platform intended to support and mobilize researchers to collaborate and conduct studies focused on fibrosis. This program is expected to expand knowledge on fibrosis and lead to potentially groundbreaking discoveries that could open up new therapeutic opportunities. “In many…
Lately, I’ve noticed I’m not thinking through things as well as I used to. It is very hard for me to accept since clear thinking was a strength for me. I was diagnosed with pulmonary fibrosis four years ago. Here’s what my brain fog looks like. Forgetting information…
A recent discussion in our new Pulmonary Fibrosis News forums was about quiet hobbies that are beneficial for patients living with idiopathic pulmonary fibrosis (IPF). As the forum’s moderator, I shared a post about my own quiet hobbies and asked patients to share some of the relaxing…
Treatment with regulatory T-cells (Tregs), a subset of cells from the immune system, is able to resolve lung fibrosis in a mouse model of idiopathic pulmonary fibrosis (IPF), according to researchers. Their findings support additional investigation of cell-based therapies to treat IPF in…
At least 800 people representing some 45 countries are soon expected to gather in Austria’s capital city, Vienna, for ECRD 2018, the 9th European Conference on Rare Diseases and Orphan Products. The May 10-12 meeting is sponsored by Eurordis, the Paris-based group that defines itself as a “patient-driven alliance”…
A combined treatment, pirfenidone and rapamycin, worked to prevent fibrosis in lung fibroblasts from patients with idiopathic pulmonary fibrosis, new research showed, suggesting a possibly more effective way of treating IPF. The study, “Anti-fibrotic effects of pirfenidone and…
